广州化工
廣州化工
엄주화공
GUANGZHOU CHEMICAL INDUSTRY AND TECHNOLOGY
2012年
13期
3-4,11
,共3页
超临界流体%超临界快速膨胀法%药物微粒
超臨界流體%超臨界快速膨脹法%藥物微粒
초림계류체%초림계쾌속팽창법%약물미립
supercritical fluids%rapid expansion of supercritical fluids method%drug rricroparticles
药物颗粒尺寸对药物生物利用度有很大影响,通过减小颗粒粒径可以提高药物的生物利用度。本文主要介绍了超临界药物微细化的方法和药物的选择性。超临界流体快速膨胀法(RESS)的原理、过程及最新的研究进展。
藥物顆粒呎吋對藥物生物利用度有很大影響,通過減小顆粒粒徑可以提高藥物的生物利用度。本文主要介紹瞭超臨界藥物微細化的方法和藥物的選擇性。超臨界流體快速膨脹法(RESS)的原理、過程及最新的研究進展。
약물과립척촌대약물생물이용도유흔대영향,통과감소과립립경가이제고약물적생물이용도。본문주요개소료초림계약물미세화적방법화약물적선택성。초림계류체쾌속팽창법(RESS)적원리、과정급최신적연구진전。
The particle sizes of the drug were important for their bioavailability. The bicavailability can be improved by reducing the particle size. The methods and selectivity of the drug using supercritical fluid,, were reviewed. The princi- ple, process and the latest research progress of the rapid expansion of supercritical fluids method (RESS) were introduced too.