CAJ | 학술논문

用共沉淀法制备Fe304磁性粒子，选用聚乙二醇和琼脂制备核／双壳医用磁性微球．最佳工艺条件为：Fe2＋／Fe2＋之比在1．70～1．75；沉淀剂25％NH3·H2O过量20～30％，在温度35℃，pH值11，反应时间为1h；琼脂的包覆最佳温度为50℃，pH值为9，时间lh；聚乙二醇包裹最佳温度为55℃，pH值为4，时间1h，可以通过调节搅拌速度和超声波分散时间控制Fe3O4粒子的尺度，实验确定包覆剂用量．并用透射电镜、分光光度计、古埃磁天平等进行了初步表征．
용공침정법제비Fe304자성입자，선용취을이순화경지제비핵／쌍각의용자성미구．최가공예조건위：Fe2＋／Fe2＋지비재1．70～1．75；침정제25％NH3·H2O과량20～30％，재온도35℃，pH치11，반응시간위1h；경지적포복최가온도위50℃，pH치위9，시간lh；취을이순포과최가온도위55℃，pH치위4，시간1h，가이통과조절교반속도화초성파분산시간공제Fe3O4입자적척도，실험학정포복제용량．병용투사전경、분광광도계、고애자천평등진행료초보표정．
Fe3O4 magnetic microsphere was prepared by coprecipitation method and medical nucleonic/bivalve mag- netic microsphere was prepared by polyethylene glycol or agar. The optimal condition of prepared Fe3O4 magnetic microsphere was that the ratio of Fe3＋/Fe2＋ was between 1.70 20 -30%, and the reaction time was lh at 35℃, and pH ic/bivalve magnetic microsphere was that the coating time time with polyethylene glycol was lh at 55℃, pH with 4. and 1.75; 25% NH3 H2O precipitant was above value was 11. The optimal condition of medical nucleon- with agar was lh at 50℃, pH with 9, and the coating The size of Fe3O4 was controlled by stirring speed and ul- trasonic. The characterizations of materials were investigated by projection electron microscopy, spectrophotometer and magnetic balance.