中华消化外科杂志
中華消化外科雜誌
중화소화외과잡지
CHINESE JOURNAL OF DIGESTIVE SURGERY
2013年
1期
25-29
,共5页
胃肿瘤%外科技术%消化道重建%循证医学%生命质量
胃腫瘤%外科技術%消化道重建%循證醫學%生命質量
위종류%외과기술%소화도중건%순증의학%생명질량
Gastric neoplasms%Surgical techniques%Digestive tract reconstruction%Evidence-based medicine%Quality of life
随着现代外科治疗效果的提高,患者术后生命质量越来越受到重视.其中消化道重建方式是患者术后生命质量最相关的因素.目前的证据表明:食管-空肠储袋Roux-en-Y吻合在全胃切除术中应用较合适;Roux-en-Y吻合在远端胃大部切除术的消化道重建中可能具有一定优势;保留幽门的胃大部切除术和近端胃大部切除术只考虑在早期胃癌(cT1cN0)中采用,保留幽门的胃大部切除术并不完全优于远端胃大部切除术;对于预期寿命相对较短、全身状况差、高龄、不可切除肿瘤、伴幽门梗阻的患者考虑内镜下支架置入;而预期寿命可相对延长的患者仍推荐Devine胃癌旷置+胃空肠短路术.然而,由于目前获得的证据级别还不高,对于现有各种胃癌消化道重建方式尚不能得出明确的评价,还需要高质量的研究结果来进一步论证.
隨著現代外科治療效果的提高,患者術後生命質量越來越受到重視.其中消化道重建方式是患者術後生命質量最相關的因素.目前的證據錶明:食管-空腸儲袋Roux-en-Y吻閤在全胃切除術中應用較閤適;Roux-en-Y吻閤在遠耑胃大部切除術的消化道重建中可能具有一定優勢;保留幽門的胃大部切除術和近耑胃大部切除術隻攷慮在早期胃癌(cT1cN0)中採用,保留幽門的胃大部切除術併不完全優于遠耑胃大部切除術;對于預期壽命相對較短、全身狀況差、高齡、不可切除腫瘤、伴幽門梗阻的患者攷慮內鏡下支架置入;而預期壽命可相對延長的患者仍推薦Devine胃癌曠置+胃空腸短路術.然而,由于目前穫得的證據級彆還不高,對于現有各種胃癌消化道重建方式尚不能得齣明確的評價,還需要高質量的研究結果來進一步論證.
수착현대외과치료효과적제고,환자술후생명질량월래월수도중시.기중소화도중건방식시환자술후생명질량최상관적인소.목전적증거표명:식관-공장저대Roux-en-Y문합재전위절제술중응용교합괄;Roux-en-Y문합재원단위대부절제술적소화도중건중가능구유일정우세;보류유문적위대부절제술화근단위대부절제술지고필재조기위암(cT1cN0)중채용,보류유문적위대부절제술병불완전우우원단위대부절제술;대우예기수명상대교단、전신상황차、고령、불가절제종류、반유문경조적환자고필내경하지가치입;이예기수명가상대연장적환자잉추천Devine위암광치+위공장단로술.연이,유우목전획득적증거급별환불고,대우현유각충위암소화도중건방식상불능득출명학적평개,환수요고질량적연구결과래진일보론증.
With the improvement of survival outcome by modern surgical treatment,more and more attention has been paid to the postoperative quality of life.As known,the most related factor of postoperative quality of life is the pattern of digestive tract reconstruction.Current evidences indicate that Roux-en-Y esophagojejunostomy + jejunal pouch has some advantages in total gastrectomy and Roux-en-Y gastrojejunostomy might be most suitable reconstruction in distal gastrectomy.Pylorns-preserving gastrectomy and proximal gastrectomy are only considered in early gastric cancer,i.e.predictive cTlcN0.Pylorus-preserving gastrectomy does not exactly superior to distal gastrectomy.Total gastrectomy with Roux-en-Y esophagojejunostomy is superior to proximal gastrectomy with esophagogastrostomy.For unresectable lower tumor with gastric outlet obstruction,gastric cancer Devine exclusion + gastrojejunostomy might be better than simple gastrojejunostomy,while stent placement is safer and suitable for predictively short-term survival,poor performance status or senility patients.However,the current available evidences of reconstruction in gastric cancer surgery is still poor in quality and more high-quality large-scale multi-center randomized controlled trials are required to resolve the controversies.