CAJ | 학술논문

目的调查化妆品变应原种类,为化妆品过敏提供流行病学资料和临床依据.方法对89例门诊疑诊化妆品变应性接触性皮炎患者采用49种欧洲化妆品系列变应原及5种中国筛查系列化妆品变应原进行斑贴试验,按国际接触性皮炎研究组推荐标准判读结果.结果 89例患者中,61例对1种或1种以上化妆品变应原过敏,阳性反应率68.5%.其中阳性率较高的有香料33.7%,防腐剂30.3%,对苯二胺25.8%,阿莫醇10.1%.结论香料、防腐剂、对苯二胺、阿莫醇等是化妆品变应性接触性皮炎患者的主要致敏原.
목적 조사화장품변응원충류,위화장품과민제공류행병학자료화림상의거.방법 대89례문진의진화장품변응성접촉성피염환자채용49충구주화장품계렬변응원급5충중국사사계렬화장품변응원진행반첩시험,안국제접촉성피염연구조추천표준판독결과.결과 89례환자중,61례대1충혹1충이상화장품변응원과민,양성반응솔68.5%.기중양성솔교고적유향료33.7%,방부제30.3%,대분이알25.8%,아막순10.1%.결론 향료、방부제、대분이알、아막순등시화장품변응성접촉성피염환자적주요치민원.
Objective To make a survey on common cosmetic allergens, and to provide epidemiological data and clinical evidence for cosmetic allergy. Methods Patch test was performed by using 49cosmetic allergens from a European cosmetic series and 5 Chinese standard screening allergens on 89patients with suspected cosmetic allergic contact dermatitis. Test results were determined according to the International Contact Dermatitis Research Group (ICDRG) recommendation. Results Of the 89 patients, 61(68.5%) showed positive reactions to one or more cosmetic allergens. The most common allergens were fragrances (33.7%), followed by preservatives (30.3%), para-phenylenediamine (25.8%) and amerchol L 101(10.1%). Conclusion Fragrances, preservatives, para-phenylenediamine and amerchol L 101 are dominant causative allergens in patients with cosmetic allergic contact dermatitis.