医学美学美容（中旬刊）
醫學美學美容（中旬刊）
의학미학미용（중순간）
MEDICAL AESTHETICS AND COSMETOLOGY
2014年
4期
1-1
,共1页
张列女%邓列华%徐瑾%李克俭%李诗娜
張列女%鄧列華%徐瑾%李剋儉%李詩娜
장열녀%산렬화%서근%리극검%리시나
伊曲康唑%2％酮康唑乳%股癣
伊麯康唑%2％酮康唑乳%股癬
이곡강서%2％동강서유%고선
] ItraconazoleCapsules%2％ ketoconazolecream%Tinea cruris
目的：探究伊曲康唑联合2%酮康唑乳膏治疗股癣的临床疗效。方法：选取94例足癣患者，随机分为治疗组(口服伊曲康唑胶囊200mg 每天1次，联合外用2%酮康唑乳膏每天2次)；对照组(单纯外用2%酮康唑乳膏每天2次)，用药疗程均为4周。观察两组患者用药后2周及4周的临床疗效和真菌学疗效及不良反应。结果：用药后2周治疗组和对照组总有效率分别为25.5%、17.0%，真菌清除率分别为25.5%、17.0%，两组比较差异无统计学意义(P>0.05)；用药后4周治疗组和对照组总有效率分别为61.7%、40.4%，真菌清除率分别为68.1%、44.7%，两组比较差异有统计学意义(P<0.05)。两组患者用药后均无严重不良反应发生。结论：口服伊曲康唑胶囊联合外用2%酮康唑乳膏比单纯外用2%酮康唑乳膏治疗股癣近期临床疗效好，且副作用少，是临床治疗股癣疗效较好的方法之一。
目的：探究伊麯康唑聯閤2%酮康唑乳膏治療股癬的臨床療效。方法：選取94例足癬患者，隨機分為治療組(口服伊麯康唑膠囊200mg 每天1次，聯閤外用2%酮康唑乳膏每天2次)；對照組(單純外用2%酮康唑乳膏每天2次)，用藥療程均為4週。觀察兩組患者用藥後2週及4週的臨床療效和真菌學療效及不良反應。結果：用藥後2週治療組和對照組總有效率分彆為25.5%、17.0%，真菌清除率分彆為25.5%、17.0%，兩組比較差異無統計學意義(P>0.05)；用藥後4週治療組和對照組總有效率分彆為61.7%、40.4%，真菌清除率分彆為68.1%、44.7%，兩組比較差異有統計學意義(P<0.05)。兩組患者用藥後均無嚴重不良反應髮生。結論：口服伊麯康唑膠囊聯閤外用2%酮康唑乳膏比單純外用2%酮康唑乳膏治療股癬近期臨床療效好，且副作用少，是臨床治療股癬療效較好的方法之一。
목적：탐구이곡강서연합2%동강서유고치료고선적림상료효。방법：선취94례족선환자，수궤분위치료조(구복이곡강서효낭200mg 매천1차，연합외용2%동강서유고매천2차)；대조조(단순외용2%동강서유고매천2차)，용약료정균위4주。관찰량조환자용약후2주급4주적림상료효화진균학료효급불량반응。결과：용약후2주치료조화대조조총유효솔분별위25.5%、17.0%，진균청제솔분별위25.5%、17.0%，량조비교차이무통계학의의(P>0.05)；용약후4주치료조화대조조총유효솔분별위61.7%、40.4%，진균청제솔분별위68.1%、44.7%，량조비교차이유통계학의의(P<0.05)。량조환자용약후균무엄중불량반응발생。결론：구복이곡강서효낭연합외용2%동강서유고비단순외용2%동강서유고치료고선근기림상료효호，차부작용소，시림상치료고선료효교호적방법지일。
Objective:Objective:To observe the ef icacy of ora lItraconazole Capsules combined with external use 2% ketoconazole cream treating tinea cruris. Methods:94 patients with tinea cruris ,were randomly divided into treatment group and control group . Treatment group oral Itraconazole Capsules combined with externaluse 2% ketoconazole cream treating 47patients with tinea cruris ,the total course of 4 weeks . Control group external use 2% ketoconazole cream treating 47 patients with tinea cruris ,the total course of 4 weeks . Observe two groups of patients with drug use 2 weeks and 4 weeks of clinical curative ef ect and mycology curative ef ect and adverse reactions . Results:Two groups of patients with druguse 2 weeks the ef ective rate were25. 5%and 17. 0 % respectively ,the fung use radication rate were 25. 5% and17. 0% respectively . There was no statistical y significant dif erence comparing the two groups(P﹥0. 05) . Two groups of patients with drug use 4 weeks the ef ective rate were 61. 7% and 40. 4% respectively ,the fung use radication rate were 68. 1% and 44. 7% respectively . Comparative dif erences between the two groups have statistical significance(P< 0. 05). Two groups of patients with no serious adverse reaction after taking this medicine. Conclusion:Oral Itraconazole Capsules combined with exter-nal use 2%ketoconazole cream in the treatment of tinea cruris clinical curative ef ect is good ,Side ef ects are less .
