中国伤残医学
中國傷殘醫學
중국상잔의학
CHINESE JOURNAL OF TRAUMA AND DISABILITY MEDICINE
2014年
1期
29-31
,共3页
预胶化淀粉%抗张强度%崩解剂%粘合剂
預膠化澱粉%抗張彊度%崩解劑%粘閤劑
예효화정분%항장강도%붕해제%점합제
Pregelatinized starch%Tensile Strength%Disintegrant%Adhesives
目的：测定不同厂家生产的预胶化淀粉的性能并选择最适合做片剂辅料的预胶化淀粉。方法：以冷水溶解度，膨润体积，水分含量，片重差异，硬度测试，崩解时限为指标，比较了3个厂家生产的预胶化淀粉的溶解性，膨胀性和可压性。结果：8g预胶化淀粉在100ml纯化水中的膨润体积基本能达到54ml，在冷水中的溶解度最高可达到27．58％，不同厂家的预胶化淀粉水分含量分别为8．14％，8．16％，6．45％，抗张强度在1．59±0．21到4．20±0．19之间，崩解时限在3～7分钟内。结论：在膨胀性，溶解性，颗粒水分，抗张强度，4个方面，第3个厂家的预胶化淀粉优于其他2个厂家；在崩解时限方面，第1个厂家的预胶化淀粉优于其他2个厂家。
目的：測定不同廠傢生產的預膠化澱粉的性能併選擇最適閤做片劑輔料的預膠化澱粉。方法：以冷水溶解度，膨潤體積，水分含量，片重差異，硬度測試，崩解時限為指標，比較瞭3箇廠傢生產的預膠化澱粉的溶解性，膨脹性和可壓性。結果：8g預膠化澱粉在100ml純化水中的膨潤體積基本能達到54ml，在冷水中的溶解度最高可達到27．58％，不同廠傢的預膠化澱粉水分含量分彆為8．14％，8．16％，6．45％，抗張彊度在1．59±0．21到4．20±0．19之間，崩解時限在3～7分鐘內。結論：在膨脹性，溶解性，顆粒水分，抗張彊度，4箇方麵，第3箇廠傢的預膠化澱粉優于其他2箇廠傢；在崩解時限方麵，第1箇廠傢的預膠化澱粉優于其他2箇廠傢。
목적：측정불동엄가생산적예효화정분적성능병선택최괄합주편제보료적예효화정분。방법：이랭수용해도，팽윤체적，수분함량，편중차이，경도측시，붕해시한위지표，비교료3개엄가생산적예효화정분적용해성，팽창성화가압성。결과：8g예효화정분재100ml순화수중적팽윤체적기본능체도54ml，재랭수중적용해도최고가체도27．58％，불동엄가적예효화정분수분함량분별위8．14％，8．16％，6．45％，항장강도재1．59±0．21도4．20±0．19지간，붕해시한재3～7분종내。결론：재팽창성，용해성，과립수분，항장강도，4개방면，제3개엄가적예효화정분우우기타2개엄가；재붕해시한방면，제1개엄가적예효화정분우우기타2개엄가。
Objective:To assay different manufacturers pregelatinized starch performance and Select the most suitable pregelatinized starch to tablet .Method:Solubility in cold water , swelling volume , moisture content , weight variation , hardness testing , disintegration as an indicator to compare with solubility , swelling and compressibility of three manufacturers of pregelatinized starch .Result:8g pregelati-nized starch swelling of volume to achieve basic 54ml in 100ml purified water, the Solubility in cold water can reach 27.58%.The water content of different manufacturers pregelatinized starch was 8.14%,8.16%, 6.45%.Tensile Strength between with 1.59 ±0.21 and 4. 20 ±0.19 and disintegration in 3-7 minutes.Conclusion:By comparing various indicators , In the expansion, solubility, particle mois-ture, tensile strength, The third manufacturers better than the other two manufacturers .In the disintegration, the first manufacturers of pre-gelatinized starch is better than the other two manufacturers .
