CAJ | 학술논문

目的：通过回顾性分析肺泡蛋白沉积症（ Pulmonary alveolar proteinosis ， PAP）的64层螺旋CT表现，探讨64层螺旋CT快速容扫描（ VCT）在肺泡蛋白沉积症诊断中的应用价值，旨在提高对本病的CT诊断水平。方法：本组所有病例均行64层CT快速容积扫描，其中4例行CT导引下经皮肺穿刺活检，8例行肺泡灌洗，4例经纤维支气管镜活检，均得到病理证实。结果：HRCT表现：两肺散在或弥漫性斑片状磨玻璃影、边界清楚（“地图样”改变），小叶间隔增厚交织（“铺路石样”改变）及实变区“空气支气管征”。结论：肺泡蛋白沉积症的HRCT表现具有相对特征性，充分了解肺泡蛋白沉积症的VCT表现，并做相关疾病的鉴别诊断，能很大程度提高对本病诊断的准确率，最终诊断依靠肺部穿刺或肺泡灌洗后确诊。
목적：통과회고성분석폐포단백침적증（ Pulmonary alveolar proteinosis ， PAP）적64층라선CT표현，탐토64층라선CT쾌속용소묘（ VCT）재폐포단백침적증진단중적응용개치，지재제고대본병적CT진단수평。방법：본조소유병례균행64층CT쾌속용적소묘，기중4례행CT도인하경피폐천자활검，8례행폐포관세，4례경섬유지기관경활검，균득도병리증실。결과：HRCT표현：량폐산재혹미만성반편상마파리영、변계청초（“지도양”개변），소협간격증후교직（“포로석양”개변）급실변구“공기지기관정”。결론：폐포단백침적증적HRCT표현구유상대특정성，충분료해폐포단백침적증적VCT표현，병주상관질병적감별진단，능흔대정도제고대본병진단적준학솔，최종진단의고폐부천자혹폐포관세후학진。
Objective:To retrospectively analysis of pulmonary alveolar proteinosis ( Pulmonary alveolar proteinosis , PAP) 64 layer spiral CT manifestations , to explore the application value of 64 slice spiral CT in the diagnosis of pulmonary alveolar proteinosis , aimed at improving the CT diagnostic level of this disease .Methods:The 16 cases of pulmonary alveolar proteinosis patients proeeded 64 layer spiral CT fast volume scanning , 4 cases with percutaneous lung biopsy with VCT induct , 8 cases with bronchoalveolar lavage , 4 cases with transbronchial biopsy , are pathology.Results:VCT findings included diffused or scattered ground glass -like images, clear boundary (“map-like” change ) , interlobular septal thickening and interleaving ( cobblestone-like change ) ,the area of consolidation “air bron-chogram”.Conclusion:VCT manifestation of PAP has relative characteristics .Understanding the VCT features of pulmonary alveolar pro-teinosis, it can greatly improve the accuracy of the diagnosis .The final diagnosis depends on the lung puncture or bronchoalveolar lavage confirmed.