CAJ | 학술논문

目的：探讨复治耐多药肺结核病（MDR-TB）的治疗，为改善其治疗效果与防治对策提供科学依据。方法427例复治MDR-TB患者按照不同的治疗方法分为3组，Ⅰ组为常规治疗组，Ⅱ组为耐多药治疗组，Ⅲ组为外科治疗组，对3组患者进行统计分析。结果常规治疗组和耐多药治疗组的痰菌转阴率、病灶吸收率和空洞闭合率分别由39．2％、42．5％和43．8％提高到72．5％、84．3％和80．4％。结论制定合理有效的化疗方案或借助外科手术治疗对控制耐多药肺结核病是十分重要的。
목적：탐토복치내다약폐결핵병（MDR-TB）적치료，위개선기치료효과여방치대책제공과학의거。방법427례복치MDR-TB환자안조불동적치료방법분위3조，Ⅰ조위상규치료조，Ⅱ조위내다약치료조，Ⅲ조위외과치료조，대3조환자진행통계분석。결과상규치료조화내다약치료조적담균전음솔、병조흡수솔화공동폐합솔분별유39．2％、42．5％화43．8％제고도72．5％、84．3％화80．4％。결론제정합리유효적화료방안혹차조외과수술치료대공제내다약폐결핵병시십분중요적。
Objective To explore the diagnosis and treatment of retreatment of multidrug-resistant tuberculosis and provide a certain scientific basis for effective prevention and control countermeasures in order to improve the treatment effect.Methods A total of 427 cases of recurrent drug-resistant tuberculosis patients who underwent different treatments were divided into three groups and the retrospective statistical analysis was carried on in our hospital from 201 1 to 2012.Results Sputum bacteria turn rate,lesions absorption rate and cavity closure rate of patients in the routine treatment group and multidrug resistant group increased from 39.2%,42.5% and 39.2% to 72.5%,84.3% and 80.4% respectively.Conclusion The formulation of rational and effective chemotherapy scheme or the aid of surgical treatment is very im-portant in controlling multidrug-resistant tuberculosis.