国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2014年
9期
1169-1171
,共3页
生化检测指标%测量不确定度%“自上而下”方法
生化檢測指標%測量不確定度%“自上而下”方法
생화검측지표%측량불학정도%“자상이하”방법
biochemical detection indicators%measurement uncertainty%“top-down” method
目的：探讨“自上而下”方法在评定临床生化指标的测量不确定度中的应用。方法利用室内质控和室间质评数据，采用“自上而下”方法评定26个生化指标的精密度和正确度，综合以上2个变量合成测量不确定度。结果18个生化指标的不确定度符合目标不确定度要求，约占所有评估项目69．2％，TBIL、清蛋白、CK、钙、镁5个指标不符合目标不确定度要求，约占总评估项目19．2％。结论采用“自上而下”方法评定生化指标的测量不确定度有效、可行。
目的：探討“自上而下”方法在評定臨床生化指標的測量不確定度中的應用。方法利用室內質控和室間質評數據，採用“自上而下”方法評定26箇生化指標的精密度和正確度，綜閤以上2箇變量閤成測量不確定度。結果18箇生化指標的不確定度符閤目標不確定度要求，約佔所有評估項目69．2％，TBIL、清蛋白、CK、鈣、鎂5箇指標不符閤目標不確定度要求，約佔總評估項目19．2％。結論採用“自上而下”方法評定生化指標的測量不確定度有效、可行。
목적：탐토“자상이하”방법재평정림상생화지표적측량불학정도중적응용。방법이용실내질공화실간질평수거，채용“자상이하”방법평정26개생화지표적정밀도화정학도，종합이상2개변량합성측량불학정도。결과18개생화지표적불학정도부합목표불학정도요구，약점소유평고항목69．2％，TBIL、청단백、CK、개、미5개지표불부합목표불학정도요구，약점총평고항목19．2％。결론채용“자상이하”방법평정생화지표적측량불학정도유효、가행。
Objective To investigate the application of “top-down” method in assessment of measurement uncertainty of bio-chemical detection indicators .Methods The assessment data of internal quality control and external quality and “top-down”method were used to assess the precision and accuracy of 26 biochemical indicators ,and the two variables above were combined to calculate the measurement uncertainty .Results Uncertainty of 18 biochemical indicators was compatible with the target uncertainty ,ac-counting for approximately 69 .2% of all assessment projects .Five indicators ,such as TBIL ,albumin ,CK ,calcium and magnesium , was not compatible with the target uncertainty ,accounting for approximately 19 .2% of all assessment projects .Conclusion The“top-down” method is effective and feasible for assessment of measurement uncertainty of biochemical detection indicators .
