CAJ | 학술논문

为探讨受试菌菌悬液浓度对体外药敏实验结果的影响,该文采用微量稀释法测定阿莫西林/克拉维酸（4：1）、庆大霉素、多西环素和恩诺沙星等4种药物对鸡大肠杆菌和鸡金黄色葡萄球菌在不同菌悬液浓度（10^3CFU/mL、10^4CFU/mL、10^5CFU/mL、10^6CFU/mL、10^7CFU/mL）的最小抑菌浓度（MIC）值。结果表明：恩诺沙星对两类细菌的MIC值不受接种的菌悬液浓度影响;多西环素对大肠杆菌的MIC值受菌悬液浓度影响较小,但其对金黄色葡萄球菌的MIC值随菌悬液浓度升高而升高;阿莫西林/克拉维酸（2：1）和阿米卡星对两类菌株的MIC值均随菌悬液浓度增大而增大,增大的幅度因药物和受试菌不同而异。
위탐토수시균균현액농도대체외약민실험결과적영향,해문채용미량희석법측정아막서림/극랍유산（4：1）、경대매소、다서배소화은낙사성등4충약물대계대장간균화계금황색포도구균재불동균현액농도（10^3CFU/mL、10^4CFU/mL、10^5CFU/mL、10^6CFU/mL、10^7CFU/mL）적최소억균농도（MIC）치。결과표명：은낙사성대량류세균적MIC치불수접충적균현액농도영향;다서배소대대장간균적MIC치수균현액농도영향교소,단기대금황색포도구균적MIC치수균현액농도승고이승고;아막서림/극랍유산（2：1）화아미잡성대량류균주적MIC치균수균현액농도증대이증대,증대적폭도인약물화수시균불동이이。
The minimum inhibitory concentrations （MICs） of amoxicillin/clavulanic acid（4/1 ）, gentamicin, deoxycycline, and enrofloxaein were detected with microdilution method against Escherichia eoli and Staphylococcus aureus strains isolated from chickens at different inoeulum suspension concentrations（10^3CFU/mL, 10^4CFU/mL, 10^5CFU/mL, 10^6CFU/mL and 10^7CFU/mL）. The results revealed that the inoculum suspension concentrations had no influence on the MICs of enrofloxacin, a little influence on the MIC of deoxycycline against Escherichia coli, but striking effect on the MICs of others. MICs were increasing with the inoculum suspension concentrations