中华生物医学工程杂志
中華生物醫學工程雜誌
중화생물의학공정잡지
CHINESE JOURNAL OF BIOMEDICAL ENGINEERING
2012年
5期
399-401
,共3页
腹膜透析,持续不卧床%死亡%危险因素
腹膜透析,持續不臥床%死亡%危險因素
복막투석,지속불와상%사망%위험인소
Peritoneal dialysis,Continuous ambulatory%Death%Risk factors
目的 分析腹膜透析患者死亡及其危险因素.方法 对河北医科大学第三医院1997至2011年透龄6个月以上的153例CAPD患者进行回顾性分析,采用多变量Cox回归分析方法分析透析患者各临床指标对预后的影响.结果 原发病病因中糖尿病肾病患者病死率最高(72.09％,31/43),其次为缺血性肾病(60.00％,6/10)；死因中主要为心力衰竭(28.99％,20/69),其次为脑血管意外(17.39％,12/69).与存活组比较,死亡组血红蛋白(Hb)、血浆白蛋白(Alb)和总尿素清除指数(Kt/V)明显降低；年龄、脉压差、血磷及PTH水平明显升高,差异均有统计学意义(均P＜0.05).Cox回归分析结果显示患者年龄、总Kt/V、血磷、Hb、Alb水平对腹膜透析6个月以上死亡患者的相对危险度分别为1.188,0.798,2.308,2.102,0.898,均有统计学意义.结论 透析初期患者年龄、Kt/、血磷、Hb、Alb水平是CAPD死亡的独立危险因素.心脑血管疾病是CAPD患者的主要死因.
目的 分析腹膜透析患者死亡及其危險因素.方法 對河北醫科大學第三醫院1997至2011年透齡6箇月以上的153例CAPD患者進行迴顧性分析,採用多變量Cox迴歸分析方法分析透析患者各臨床指標對預後的影響.結果 原髮病病因中糖尿病腎病患者病死率最高(72.09％,31/43),其次為缺血性腎病(60.00％,6/10)；死因中主要為心力衰竭(28.99％,20/69),其次為腦血管意外(17.39％,12/69).與存活組比較,死亡組血紅蛋白(Hb)、血漿白蛋白(Alb)和總尿素清除指數(Kt/V)明顯降低；年齡、脈壓差、血燐及PTH水平明顯升高,差異均有統計學意義(均P＜0.05).Cox迴歸分析結果顯示患者年齡、總Kt/V、血燐、Hb、Alb水平對腹膜透析6箇月以上死亡患者的相對危險度分彆為1.188,0.798,2.308,2.102,0.898,均有統計學意義.結論 透析初期患者年齡、Kt/、血燐、Hb、Alb水平是CAPD死亡的獨立危險因素.心腦血管疾病是CAPD患者的主要死因.
목적 분석복막투석환자사망급기위험인소.방법 대하북의과대학제삼의원1997지2011년투령6개월이상적153례CAPD환자진행회고성분석,채용다변량Cox회귀분석방법분석투석환자각림상지표대예후적영향.결과 원발병병인중당뇨병신병환자병사솔최고(72.09％,31/43),기차위결혈성신병(60.00％,6/10)；사인중주요위심력쇠갈(28.99％,20/69),기차위뇌혈관의외(17.39％,12/69).여존활조비교,사망조혈홍단백(Hb)、혈장백단백(Alb)화총뇨소청제지수(Kt/V)명현강저；년령、맥압차、혈린급PTH수평명현승고,차이균유통계학의의(균P＜0.05).Cox회귀분석결과현시환자년령、총Kt/V、혈린、Hb、Alb수평대복막투석6개월이상사망환자적상대위험도분별위1.188,0.798,2.308,2.102,0.898,균유통계학의의.결론 투석초기환자년령、Kt/、혈린、Hb、Alb수평시CAPD사망적독립위험인소.심뇌혈관질병시CAPD환자적주요사인.
Objective To analyze the risk factors and mortality of patients on continuous ambulatory peritoneal dialysis (CAPD).Methods A retrospective analysis was performed in 153 patients receiving CAPD for ＞6 months The Third Hospital,Hebei Medical University,between 1997 and 2011.The impact of clinical indices on the prognosis were determined via Cox regression analysis.Results Of all the primary causes,diabetic nephropathy (72.09％,31/43) accounted for the highest proportion,followed by ischemic nephropathy (60.00％,6/10).The cause of death was predominated by heart failure (28.99％,20/69),followed by cerebrovascular events (17.39％,12/69).The patients who subsequently died were featured by impressively lower levels of hemoglobin,serum albumin and total Kt/V,and considerably higher levels of pulse pressure,serum phosphate,and parathyroid hormone (all P＜0.05).Age,total Kt/V,serum phosphorus,hemoglobin and serum albumin yielded an OR of 1.188,0.798,2.308,2.102 and 0.898 in dead patients although having received CAPD for ＞6 months (all P＜0.05),as suggested by Cox regression analysis.Conclusion Cardiocerebro vascular event is the leading cause of death in CAPD patients,while age,total Kt/V,serum phosphorous,hemoglobin and serum albumin are independent risk factors of mortality in patients initially received CAPD.
