中华生物医学工程杂志
中華生物醫學工程雜誌
중화생물의학공정잡지
CHINESE JOURNAL OF BIOMEDICAL ENGINEERING
2012年
5期
402-405
,共4页
弱视%屈光不正%诱发电位,视觉%潜伏期%振幅
弱視%屈光不正%誘髮電位,視覺%潛伏期%振幅
약시%굴광불정%유발전위,시각%잠복기%진폭
Amblyopia%Refractive errors%Evoked potentials,visual%Latency%Amplitude
目的 对比近视性、远视性、散光性弱视患儿治疗前后的图形翻转视觉诱发电位(PRVEP),探讨不同性质屈光不正性弱视的治疗效果.方法 筛选2009年5月至2011年5月本院诊治的年龄6～7岁的弱视患儿90例,分为近视性、远视性及混合散光性3组,每组各30例60只眼,30例健康儿童60只眼作为对照,采用视觉诱发电位仪作PR-VEP检测,记录并比较弱视治疗前后各组P100潜伏期和P波振幅的变化.结果 治疗前,与健康儿童组比较,3组弱视眼组PR-VEP的P100潜伏期延长,P波振幅下降.与远视性弱视组和散光性弱视组相比,近视性弱视组P100潜伏期最长(均P＜0.05),P波振幅最低(均P＜0.05),而远视性弱视组和散光性弱视组之间差异无统计学意义.与治疗前比较,3组弱视患儿弱视眼在治疗之后P100的潜伏期缩短,P波振幅上升.近视性、远视性及混合散光性3组弱视患儿治疗前后的潜伏期差值和振幅差值之间差异也有统计学意义[潜伏期差值:(2.640±0.009) ms比(5.590±0.576)ms比(6.989±2.229)ms,振幅差值:(0.929±0.611)μV比(2.595±0.464) μV比(2.575±0.211)μV,均P＜0.05],近视性弱视的潜伏期差值和振幅差值最小.结论 近视性弱视治疗前后的潜伏期差值和振幅差值最小,证实了近视性弱视的难治性.PR-VEP检测对弱视的临床治疗具有指导意义.
目的 對比近視性、遠視性、散光性弱視患兒治療前後的圖形翻轉視覺誘髮電位(PRVEP),探討不同性質屈光不正性弱視的治療效果.方法 篩選2009年5月至2011年5月本院診治的年齡6～7歲的弱視患兒90例,分為近視性、遠視性及混閤散光性3組,每組各30例60隻眼,30例健康兒童60隻眼作為對照,採用視覺誘髮電位儀作PR-VEP檢測,記錄併比較弱視治療前後各組P100潛伏期和P波振幅的變化.結果 治療前,與健康兒童組比較,3組弱視眼組PR-VEP的P100潛伏期延長,P波振幅下降.與遠視性弱視組和散光性弱視組相比,近視性弱視組P100潛伏期最長(均P＜0.05),P波振幅最低(均P＜0.05),而遠視性弱視組和散光性弱視組之間差異無統計學意義.與治療前比較,3組弱視患兒弱視眼在治療之後P100的潛伏期縮短,P波振幅上升.近視性、遠視性及混閤散光性3組弱視患兒治療前後的潛伏期差值和振幅差值之間差異也有統計學意義[潛伏期差值:(2.640±0.009) ms比(5.590±0.576)ms比(6.989±2.229)ms,振幅差值:(0.929±0.611)μV比(2.595±0.464) μV比(2.575±0.211)μV,均P＜0.05],近視性弱視的潛伏期差值和振幅差值最小.結論 近視性弱視治療前後的潛伏期差值和振幅差值最小,證實瞭近視性弱視的難治性.PR-VEP檢測對弱視的臨床治療具有指導意義.
목적 대비근시성、원시성、산광성약시환인치료전후적도형번전시각유발전위(PRVEP),탐토불동성질굴광불정성약시적치료효과.방법 사선2009년5월지2011년5월본원진치적년령6～7세적약시환인90례,분위근시성、원시성급혼합산광성3조,매조각30례60지안,30례건강인동60지안작위대조,채용시각유발전위의작PR-VEP검측,기록병비교약시치료전후각조P100잠복기화P파진폭적변화.결과 치료전,여건강인동조비교,3조약시안조PR-VEP적P100잠복기연장,P파진폭하강.여원시성약시조화산광성약시조상비,근시성약시조P100잠복기최장(균P＜0.05),P파진폭최저(균P＜0.05),이원시성약시조화산광성약시조지간차이무통계학의의.여치료전비교,3조약시환인약시안재치료지후P100적잠복기축단,P파진폭상승.근시성、원시성급혼합산광성3조약시환인치료전후적잠복기차치화진폭차치지간차이야유통계학의의[잠복기차치:(2.640±0.009) ms비(5.590±0.576)ms비(6.989±2.229)ms,진폭차치:(0.929±0.611)μV비(2.595±0.464) μV비(2.575±0.211)μV,균P＜0.05],근시성약시적잠복기차치화진폭차치최소.결론 근시성약시치료전후적잠복기차치화진폭차치최소,증실료근시성약시적난치성.PR-VEP검측대약시적림상치료구유지도의의.
Objective To compare the features of pattern reversal visual-evoked potential (PRVEP) in children with myopic,hypermetropic and astigmatical amblyopia and the effect of treatment on PRVEP.Methods Ninty children (180 eyes) with amblyopia at 6 to 7 years of age were recruited from Guangzhou Women and Children' s Medical Center between May 2009 and May 2011 and were assigned to myopic (n=30,60 eyes),hypermetropic (n=30,60 eyes) and astigmatical (n=30,60 eyes) amblyopia group respectively.Thirty normal healthy children (60 eyes) were served as normal controls.PR-VEP examination was undertaken for comparison on the latency period of P100 and changes in amplitude of P wave piror to and after treatment.Results Children with amblyopia were associated with prolonged latency period of P100 for PR-VEP and reduced amplitude of P wave as compared with normal controls.Children with myopic amblyopia possessed the longest latency period of P100 and the lowest amplitude of P wave (both P＜0.05),followed by those with hypermetropic and astigmatical amblyopia (P＞0.05 for between-group comparison).Shortened latency period of P100 and increased amplitude of P wave were noted after the treatment in children with amblyopia.The differences in pre-and post-treatment latency period of P100 and amplitude of P wave reached statistical significance among the three groups [for the difference in latency period:(2.640±0.009 ms vs (5.590±0.576)ms vs (6.989±2.229)ms,for the difference in amplitude of P wave:(0.929 ± 0.611) μV vs (2.595 ± 0.464) μV vs (2.575 ± 0.211) μV,all P＜0.05].Children with myopic amblyopia were featured by the lowest difference in latency period and amplitude.Conclusion The fact that children with myopic amblyopia have the lowest difference in latency period and amplitude proves the refactory treatment.Asessment of PR-VEP is clinically important to the treatment of amblyopia.
