甘肃医药
甘肅醫藥
감숙의약
Gansu Medical Journal
2014年
4期
241-243
,共3页
充血性心力衰竭%益气养阴活血法%心功能%细胞因子%临床观察
充血性心力衰竭%益氣養陰活血法%心功能%細胞因子%臨床觀察
충혈성심력쇠갈%익기양음활혈법%심공능%세포인자%림상관찰
congestive heart failure%Qi-Supplementing-and-Yin-Nouri-shing-and-Blood Circulation-Activating method%cardiac function%inflammatory cytokines%clinical observation
目的：探讨益气养阴活血法对充血性心力衰竭（CHF）患者的心功能以及炎症细胞因子的影响。方法：将80例CHF患者进行随机分为两组，即治疗组和对照组，对照组应用西医常规治疗，治疗组以此为基础，配合益气养阴活血法进行治疗，疗程均为4周。治疗前后分别测量两组患者左室舒张末期内径（LVEDD）、左室收缩末期内径（LVESD）、左室射血分数（LVEF）等心功能指标，以及血清肿瘤坏死因子（TNF-α）和白细胞介素-6（IL-6）水平，同时进行疗效观察。结果：治疗结束后，两组患者LVEDD、LVESD、LVEF等心功能指标均不同程度被改善，血清TNF-α和IL-6水平均有所下降，治疗组患者心功能改善情况优于对照组，血清TNF-α和IL-6水平降低幅度亦优于对照组，经比较均有显著性差异（P<0.05）。结论：在西医常规治疗基础上配合益气养阴活血法治疗CHF，可改进患者心功能，降低血清TNF-α、IL-6细胞因子水平。
目的：探討益氣養陰活血法對充血性心力衰竭（CHF）患者的心功能以及炎癥細胞因子的影響。方法：將80例CHF患者進行隨機分為兩組，即治療組和對照組，對照組應用西醫常規治療，治療組以此為基礎，配閤益氣養陰活血法進行治療，療程均為4週。治療前後分彆測量兩組患者左室舒張末期內徑（LVEDD）、左室收縮末期內徑（LVESD）、左室射血分數（LVEF）等心功能指標，以及血清腫瘤壞死因子（TNF-α）和白細胞介素-6（IL-6）水平，同時進行療效觀察。結果：治療結束後，兩組患者LVEDD、LVESD、LVEF等心功能指標均不同程度被改善，血清TNF-α和IL-6水平均有所下降，治療組患者心功能改善情況優于對照組，血清TNF-α和IL-6水平降低幅度亦優于對照組，經比較均有顯著性差異（P<0.05）。結論：在西醫常規治療基礎上配閤益氣養陰活血法治療CHF，可改進患者心功能，降低血清TNF-α、IL-6細胞因子水平。
목적：탐토익기양음활혈법대충혈성심력쇠갈（CHF）환자적심공능이급염증세포인자적영향。방법：장80례CHF환자진행수궤분위량조，즉치료조화대조조，대조조응용서의상규치료，치료조이차위기출，배합익기양음활혈법진행치료，료정균위4주。치료전후분별측량량조환자좌실서장말기내경（LVEDD）、좌실수축말기내경（LVESD）、좌실사혈분수（LVEF）등심공능지표，이급혈청종류배사인자（TNF-α）화백세포개소-6（IL-6）수평，동시진행료효관찰。결과：치료결속후，량조환자LVEDD、LVESD、LVEF등심공능지표균불동정도피개선，혈청TNF-α화IL-6수평균유소하강，치료조환자심공능개선정황우우대조조，혈청TNF-α화IL-6수평강저폭도역우우대조조，경비교균유현저성차이（P<0.05）。결론：재서의상규치료기출상배합익기양음활혈법치료CHF，가개진환자심공능，강저혈청TNF-α、IL-6세포인자수평。
Objective:To discuss the influence of Qi-Suppleme nting-and-Yin-Nourishing-and-Blood Circulation-Activating Method on cardiac function and inflammatory cytokines of patients with congestive heart failure(CHF). Methods:80 patients with CHF were randomly divided into the treatment group (40 cases) and the control group (40 cases) in which the control group was treated with routine western medicine and the treatment group was treated with decoction besides the control group therapy. Left ventricular end-diastolic diameter(LVEDD),left ventricular end systolic diameter(LVESD),left ventricular ejection fraction(LVEF) in the two group were measured before and after the 4 weeks of treatment,and the level of serum tumor necrosis factor-α(TNF-α) and interleukin-6(IL-6) were also measured, and curative effect was observed. Results:LVEDD、LVESD、LVEF in two groups were improved in different degree after treatment , serum levels of TNF-α and IL-6 were lowered significantly . The treatment group was superior to the control group in improving cardiac function,and in decreasing the blood concentrations of serum TNF-α and IL-6,and the change was more marked in the treatment group (P<0.05). Conclusion:On the basis of western medicine,treating CHF by combined with Qi-Supplementing-and-Yin-Nourishing-and-Blood Circulation-Activating method could improve the cardiac function,and lower the level of serum TNF-α and IL-6.
