CAJ | 학술논문

在以偏微分方程形式的单柱色谱分离模型基础上，结合 SMB 的各区流量和质量守恒关系，建立了模拟移动床色谱分离过程的数学模型。与通常的真实移动床模型相比，所建模型明确考虑进出料口的周期性切换，因此可以反映SMB的真实情况。基于有限差分法对模拟移动床模型数值进行了求解，并分析了操作参数的变化对其操作性能的影响。
재이편미분방정형식적단주색보분리모형기출상，결합 SMB 적각구류량화질량수항관계，건립료모의이동상색보분리과정적수학모형。여통상적진실이동상모형상비，소건모형명학고필진출료구적주기성절환，인차가이반영SMB적진실정황。기우유한차분법대모의이동상모형수치진행료구해，병분석료조작삼수적변화대기조작성능적영향。
Based on the single column partial differential equation model for the industry chromatographic separation, the mathematical model of the Simulated Moving Bed chromatographic separation process is established from the flow and mass conservation relations of the SMB process. Compared with the true moving bed model, the established model takes into consideration the periodic switch at the feed inlets and outlets, hence reflects the conditions in a true SMB process. Method of line is used for the numeric model computations, and the influence of changing operation parameters on the operation performance is analyzed.