CAJ | 학술논문

目的采用3.0T MRI诊断盆腔病变，确定双指数模型对盆腔病变的诊断价值。资料与方法50例盆腔占位患者（良性30例，恶性20例）行MR750-扩散加权成像（DWI）扫描，b值取0、50、300、600、800、1200 s/mm2，在AW 451工作站，利用Functool-MADC软件进行处理，分别记录并比较良、恶性病变Slow ADC值、Fast ADC值、Standard ADC值、Fraction of fast ADC值，并将Standard ADC图与轴位T2脂肪抑制图像融合。结果良性病变Slow ADC值[（1.83±0.86）×10-3 mm2/s]及Standard ADC值[（1.79±0.78）×10-3 mm2/s]均大于恶性病变[Slow ADC值（：1.05±0.31）×10-3 mm2/s；Standard ADC值：（1.13±0.39）×10-3 mm2/s]（t=3.90、3.51, P<0.01），且Slow ADC值在良、恶性病变间差异最大。良性病变及恶性病变Slow ADC值均显著小于Fast ADC值[良性：Slow ADC值为（1.83±0.86）×10-3 mm2/s，Fast ADC值为（16.95±8.63）×10-3 mm2/s；恶性：SlowADC值为（1.05±0.31）×10-3 mm2/s，Fast ADC值为（15.12±9.90）×10-3 mm2/s]（t=-10.40、-6.29, P<0.01）。结论双指数衰减模型能很好地鉴别诊断良、恶性盆腔肿瘤，对临床术前诊断意义重大。
목적채용3.0T MRI진단분강병변，학정쌍지수모형대분강병변적진단개치。자료여방법50례분강점위환자（량성30례，악성20례）행MR750-확산가권성상（DWI）소묘，b치취0、50、300、600、800、1200 s/mm2，재AW 451공작참，이용Functool-MADC연건진행처리，분별기록병비교량、악성병변Slow ADC치、Fast ADC치、Standard ADC치、Fraction of fast ADC치，병장Standard ADC도여축위T2지방억제도상융합。결과량성병변Slow ADC치[（1.83±0.86）×10-3 mm2/s]급Standard ADC치[（1.79±0.78）×10-3 mm2/s]균대우악성병변[Slow ADC치（：1.05±0.31）×10-3 mm2/s；Standard ADC치：（1.13±0.39）×10-3 mm2/s]（t=3.90、3.51, P<0.01），차Slow ADC치재량、악성병변간차이최대。량성병변급악성병변Slow ADC치균현저소우Fast ADC치[량성：Slow ADC치위（1.83±0.86）×10-3 mm2/s，Fast ADC치위（16.95±8.63）×10-3 mm2/s；악성：SlowADC치위（1.05±0.31）×10-3 mm2/s，Fast ADC치위（15.12±9.90）×10-3 mm2/s]（t=-10.40、-6.29, P<0.01）。결론쌍지수쇠감모형능흔호지감별진단량、악성분강종류，대림상술전진단의의중대。
Purpose To explore the diagnostic value of double exponential model for pelvic lesions using 3.0T MRI for the diagnosis of pelvic lesion. Materials and Methods Fifty patients with pelvic lesions (30 benign cases and 20 malignant cases) underwent MR750-diffusion weighted imaging (DWI) scans, with b values of 0, 50, 300, 600, 800 and 1200 s/mm2, Functool-MADC software was used on AW 451 workstations for data processing, Slow ADC value, Fast ADC value, Standard ADC value, Fraction of fast ADC value were recorded and compared between benign and malignant lesions, and Standard ADC images were fused with axial T2 fat-suppressed images. Results Slow ADC values [(1.83±0.86)×10-3 mm2/s] and Standard ADC values [(1.79±0.78)×10-3 mm2/s] of benign lesions were larger than those of the malignant lesions [Slow ADC values:(1.05±0.31)×10-3 mm2/s;Standard ADC values:(1.13±0.39)×10-3 mm2/s] (t=3.90, 3.51;P<0.01), and the difference of Slow ADC value was largest between benign and malignant lesions. Slow ADC values of both benign and malignant lesions were significantly less than the Fast ADC values [benign:Slow ADC value=(1.83±0.86)×10-3 mm2/s, Fast ADC value=(16.95±8.63)×10-3 mm2/s; malignant: Slow ADC value=(1.05±0.31)×10-3 mm2/s, Fast ADC value=(15.12±9.90)×10-3 mm2/s] (t=-10.40,-6.29;P<0.01). Conclusion Double exponential decay model is capable of differentiating benign and malignant pelvic tumors, thus is of great significance for clinical preoperative diagnosis.