医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2013年
32期
56-56,57
,共2页
喉显镜手术%预注右旋美托咪啶%麻醉效果
喉顯鏡手術%預註右鏇美託咪啶%痳醉效果
후현경수술%예주우선미탁미정%마취효과
目的：分析喉显镜手术中预注右旋美托咪啶的应用效果。方法随机选取2012年6月-2013年6月在我院实施喉显镜手术的68例患者，并将其平均分成两组，两组患者均采用雷米芬太尼和丙泊酚进行麻醉，其中在麻醉之前，对照组患者进行10ml的脂肪乳安慰剂的的静脉注射；观察组患者进行0.6 g/kg右旋美托咪啶。最后对患者在（T0）麻醉前、（T1）插管时、（T2）支撑喉镜置入时、（T3）拔管1分钟后和(T4)5分钟的NE(去甲肾上腺素)、HR以及丙泊酚用量等情况进行测定与记录。结果对照组HR、MAP以及血浆E与NE的浓度都呈明显降低现象，两组相比，差异显著，存在统计学意义（P<0.05）；对照组患者的丙泊酚用量为130±25mg,观察组患者为210±30mg，两组差异相比，差异明显，具有统计学意义（P<0.05）。结论在喉显镜手术中预注右旋美托咪啶，可以对患者的应激反应进行有效的减轻，值得推广。
目的：分析喉顯鏡手術中預註右鏇美託咪啶的應用效果。方法隨機選取2012年6月-2013年6月在我院實施喉顯鏡手術的68例患者，併將其平均分成兩組，兩組患者均採用雷米芬太尼和丙泊酚進行痳醉，其中在痳醉之前，對照組患者進行10ml的脂肪乳安慰劑的的靜脈註射；觀察組患者進行0.6 g/kg右鏇美託咪啶。最後對患者在（T0）痳醉前、（T1）插管時、（T2）支撐喉鏡置入時、（T3）拔管1分鐘後和(T4)5分鐘的NE(去甲腎上腺素)、HR以及丙泊酚用量等情況進行測定與記錄。結果對照組HR、MAP以及血漿E與NE的濃度都呈明顯降低現象，兩組相比，差異顯著，存在統計學意義（P<0.05）；對照組患者的丙泊酚用量為130±25mg,觀察組患者為210±30mg，兩組差異相比，差異明顯，具有統計學意義（P<0.05）。結論在喉顯鏡手術中預註右鏇美託咪啶，可以對患者的應激反應進行有效的減輕，值得推廣。
목적：분석후현경수술중예주우선미탁미정적응용효과。방법수궤선취2012년6월-2013년6월재아원실시후현경수술적68례환자，병장기평균분성량조，량조환자균채용뢰미분태니화병박분진행마취，기중재마취지전，대조조환자진행10ml적지방유안위제적적정맥주사；관찰조환자진행0.6 g/kg우선미탁미정。최후대환자재（T0）마취전、（T1）삽관시、（T2）지탱후경치입시、（T3）발관1분종후화(T4)5분종적NE(거갑신상선소)、HR이급병박분용량등정황진행측정여기록。결과대조조HR、MAP이급혈장E여NE적농도도정명현강저현상，량조상비，차이현저，존재통계학의의（P<0.05）；대조조환자적병박분용량위130±25mg,관찰조환자위210±30mg，량조차이상비，차이명현，구유통계학의의（P<0.05）。결론재후현경수술중예주우선미탁미정，가이대환자적응격반응진행유효적감경，치득추엄。
application analysis of laryngeal microscope operation in the pre infusion of dexmedetomidine. Methods 68 cases were randomly selected in 2012 June -2013 year in June in our hospital implementation of laryngeal microscope operation patients, which were divided into two groups, two groups of patients with remifentanil and propofol in anesthesia, the patients in control group before, 10ml fat emulsion for intravenous injection of placebo; the patients in observation group were 0.6g/kg dexmedetomidine. At the end of the patients (T0) (T1) before anesthesia, intubation, laryngoscope (T2) placement (T3), extubation after 1 minutes and 5 minutes (T4) NE (norepinephrine), HR and the dosage of propofol were measured and recorded. Results in the control group, HR, MAP and plasma E and NE concentrations were significantly reduced, compared to the two groups, significant difference, there were statistical significance (P<0.05); the control group patients with propofol dosage was 130±25mg, the patients in observation group was 210 ± 30mg, compared, differences between the two groups differed significantly, with statistical significance (P<0.05). Conclusion in laryngeal microscope operation in the pre injection of dexmedetomidine on stress response of patients, can effectively reduce, worthy of promotion.
