CAJ | 학술논문

为优化黄芩巴布剂的基质配方，以初黏性、持黏性及感官指标为综合指标，采用正交设计进行试验．结果表明，黄芩巴布剂处方中各基质及药物的最佳配比为甘油∶1，2-丙二醇∶聚丙烯酸钠∶羧甲基纤维素钠∶明胶∶黄芩浸膏＝8∶4∶4．5∶2∶3∶6．5，制得的膏体柔软，黏性适度，涂展性、保湿性良好，剥离无残留，此基质配方可用于黄芩巴布剂的制备．
위우화황금파포제적기질배방，이초점성、지점성급감관지표위종합지표，채용정교설계진행시험．결과표명，황금파포제처방중각기질급약물적최가배비위감유∶1，2-병이순∶취병희산납∶최갑기섬유소납∶명효∶황금침고＝8∶4∶4．5∶2∶3∶6．5，제득적고체유연，점성괄도，도전성、보습성량호，박리무잔류，차기질배방가용우황금파포제적제비．
To choose the optimum matrix formulation of Scutellaria Baicalensis cataplasm , orthogonal test was designed with the comprehensive indexes ,including initial adhesion ,per-manent adhesion and sensory indexes .The results of the test have shown that the optimum matrix formulation of Scutellaria Baicalensis cataplasm was glycerol ,1 ,2-propanediol ,sodi-um polyacrylate ,CMC-Na ,gelatin ,Scutellaria Baicalensis extract ,and the ratio was 8∶4∶4 .5∶2∶3∶6 .5 .The cataplasm made by the optimum matrix formulation is moderately vis-cous ,with good extension and moisture and no residue by stripping .The matrix formulation can be used to product Scutellaria Baicalensis cataplasm .