新医学
新醫學
신의학
NEW CHINESE MEDICINE
2014年
4期
226-230
,共5页
显微镜下结肠炎%胶原性结肠炎%淋巴细胞性结肠炎%腹泻
顯微鏡下結腸炎%膠原性結腸炎%淋巴細胞性結腸炎%腹瀉
현미경하결장염%효원성결장염%림파세포성결장염%복사
Microscopic Colitis%Collagenous colitis%Lymphocytic colitis%Diarrhea
显微镜下结肠炎(MC)是一种容易被错过的慢性腹泻的原因,多见于老年人,主要包括胶原性结肠炎和淋巴细胞性结肠炎两种亚型。最近报道MC的发病率呈上升趋势,其病因及机制尚未明确,但与免疫因素、药物特别是NSAID、感染、胆汁吸收障碍等有关。临床诊断需要病理活组织检查来明确。MC的治疗目的主要是缓解病情,应用氨基水杨酸、水杨酸亚铋、皮质类固醇类如布地奈德等治疗有效。
顯微鏡下結腸炎(MC)是一種容易被錯過的慢性腹瀉的原因,多見于老年人,主要包括膠原性結腸炎和淋巴細胞性結腸炎兩種亞型。最近報道MC的髮病率呈上升趨勢,其病因及機製尚未明確,但與免疫因素、藥物特彆是NSAID、感染、膽汁吸收障礙等有關。臨床診斷需要病理活組織檢查來明確。MC的治療目的主要是緩解病情,應用氨基水楊痠、水楊痠亞鉍、皮質類固醇類如佈地奈德等治療有效。
현미경하결장염(MC)시일충용역피착과적만성복사적원인,다견우노년인,주요포괄효원성결장염화림파세포성결장염량충아형。최근보도MC적발병솔정상승추세,기병인급궤제상미명학,단여면역인소、약물특별시NSAID、감염、담즙흡수장애등유관。림상진단수요병리활조직검사래명학。MC적치료목적주요시완해병정,응용안기수양산、수양산아필、피질류고순류여포지내덕등치료유효。
Microscopic colitis,composed of lymphocytic colitis and collagenous colitis,is a relatively common cause of chronic diarrhea in elder people. Recent studies have shown an increased incidence of micro-scopic colitis. The etiology is unknown,but related to immune factor,drugs-especially NSAID,infection and bile acid malabsorption.The diagnosis is based on specific histopathologic findings from colonic biopsy specimens. Therapy is directed primarily at resolving the symptoms of microscopic colitis,aminosalicylate, bismuth subsalicylate,corticosteroids such as budesonide have been effective.