CAJ | 학술논문

目的：保济丸中厚朴酚、和厚朴酚的含量测定。方法采用 Hypersil ODS 色谱柱（4．6 mm ×250 mm ，25 um），以甲醇-水（78∶22）为流动相，检测波长为294 nm ，测定厚朴酚及和厚朴酚含量。结果厚朴酚在0．226 mg ～0．133 mg 线性关系良好（ r ＝0．9999），平均回收率为97．96％，RSD 为1．80％。和厚朴酚在0．32 mg ～1．60 mg 线性关系良好（ r ＝0．9999），平均回收率为95．88％，RSD 为1．56％。结论该方法稳定，结果可靠，重复性好，可作为保济丸质量控制标准之一。
목적：보제환중후박분、화후박분적함량측정。방법채용 Hypersil ODS 색보주（4．6 mm ×250 mm ，25 um），이갑순-수（78∶22）위류동상，검측파장위294 nm ，측정후박분급화후박분함량。결과후박분재0．226 mg ～0．133 mg 선성관계량호（ r ＝0．9999），평균회수솔위97．96％，RSD 위1．80％。화후박분재0．32 mg ～1．60 mg 선성관계량호（ r ＝0．9999），평균회수솔위95．88％，RSD 위1．56％。결론해방법은정，결과가고，중복성호，가작위보제환질량공제표준지일。
Objective Magnolol and Honokiol were identified in baojiwan pills .Methods To detemine the contents of Magnolol in baoji pills by HPLC ,Hypersil ODS column was used ,and methanol water( 78 ∶ 22) as a mobilephase , the detection wave length was at 294 nm . To detemine the contents of Honokiol in baoji pills by HPLC ,Hypersil ODS column was used ,and methanol water( 78 ∶ 22) as a mobilephase ,the detection wave length was at 294 nm . Results Magnolol showed a good linear relationship at a range of 0 .266 mg - 1 .33mg ( r = 0 .9999) , The average recovery was 97 .96% and RSD was1 .80% .Honokiol showed a good linear relationship at a range of 0 .32 mg -1 .6 mg( r = 0 .9999 ) ,The average recovery was 95 .88% and RSD was 1 .56 % .Conclusion The method is accurate and reliable ,and can be used to conrrol the quality of baoji pills .