CAJ | 학술논문

目的：探讨两种不同的糖皮质激素甲泼尼龙和泼尼松在肾病综合征治疗过程感染发生率。方法回顾分析了近三年来，在我院就诊的110例原发性肾病综合征患者使用甲泼尼龙或泼尼松治疗者，将其分为甲泼尼龙组和泼尼松组，比较两者在足量激素使用期、减量期及维持缓解期2组患者感染发生率的不同。结果甲泼尼龙组及泼尼松组均有明显的感染发生率，但在激素减量阶段甲泼尼龙组较泼尼松组有更高的感染发生率，差异具有统计学意义（P ＜0．05）。结论甲泼尼龙在原发肾病综合征治疗过程中更易导致感染的发生。
목적：탐토량충불동적당피질격소갑발니룡화발니송재신병종합정치료과정감염발생솔。방법회고분석료근삼년래，재아원취진적110례원발성신병종합정환자사용갑발니룡혹발니송치료자，장기분위갑발니룡조화발니송조，비교량자재족량격소사용기、감량기급유지완해기2조환자감염발생솔적불동。결과갑발니룡조급발니송조균유명현적감염발생솔，단재격소감량계단갑발니룡조교발니송조유경고적감염발생솔，차이구유통계학의의（P ＜0．05）。결론갑발니룡재원발신병종합정치료과정중경역도치감염적발생。
Objective To analysis the infection incidence in the treatment of primary nephrotic syndrome with methylprednisolone and prednisone . Methods 110 primary nephrotic syndrome patients were treated with methylprednisolone or prednisone in the recent 3 years in our hospital . It can be divided into methyl prednisolone group and prednisone group , To analysis the infection incidence of the in two groups in the stage of the full amount of hormones , reduction period and maintain remission .Results The incidence of infection were obviously in methylprednisolone group and prednisone group , but methylprednisolone group had a higher incidence of infection in the hormone reduction period , the difference is statistically significant (P < 0 .05 ) .Conclusion methylprednisolone are more likely to cause infection during the treatment of primary nephrotic syndrome .