CAJ | 학술논문

采用天然交联剂京尼平，结合相分离技术与冷冻干燥方法，制备不同交联度的明胶多孔支架。结果表明，支架的交联度随着京尼平浓度的增加而升高，最高可以达到65.3％；不同交联度的明胶支架微观呈相互连通的多孔结构，且孔径随交联度的升高而降低；通过调控明胶支架的交联度，可以调控支架的降解时间。
채용천연교련제경니평，결합상분리기술여냉동간조방법，제비불동교련도적명효다공지가。결과표명，지가적교련도수착경니평농도적증가이승고，최고가이체도65.3％；불동교련도적명효지가미관정상호련통적다공결구，차공경수교련도적승고이강저；통과조공명효지가적교련도，가이조공지가적강해시간。
Genipin crosslinked gelatin scaffolds with different crosslinking degrees were fabricated using phase separation technique and a freeze-drying method.The results indicated the crosslinking degrees were increased to 65.3%when the concentration of genipin was 20 mg/mL.The scaffold displayed high interconnected porous micro-structure and the pore size was decreased at a low crosslinking degree.In vitro degradation test showed the degrada-tion rate was controlled by crosslinking degree of gelatin scaffold.