CAJ | 학술논문

目的：探讨中药注射剂不良反应发生特点、常见原因及防治措施。方法通过检索2012～2013年期刊文献及不良反应监测中心报道，应用文献计量学方法对245例中药注射剂不良反应详细病案进行整理与分析。结果所有病例中男148例（60.4％），女97例（39.6％）；发生率最高为＞60岁，占23.7％，最低20～30岁，占8.2％；不良反应主要发生在心血管疾病类以及清热解毒类这两类中药注射剂中；其中双黄连注射剂发生率最高为9.8％；最常见不良反应为过敏反应以及皮肤性反应（56.3％）。结论通过提高中药注射剂的质量以及正确选择能够减少患者不良反应的发生。
목적：탐토중약주사제불량반응발생특점、상견원인급방치조시。방법통과검색2012～2013년기간문헌급불량반응감측중심보도，응용문헌계량학방법대245례중약주사제불량반응상세병안진행정리여분석。결과소유병례중남148례（60.4％），녀97례（39.6％）；발생솔최고위＞60세，점23.7％，최저20～30세，점8.2％；불량반응주요발생재심혈관질병류이급청열해독류저량류중약주사제중；기중쌍황련주사제발생솔최고위9.8％；최상견불량반응위과민반응이급피부성반응（56.3％）。결론통과제고중약주사제적질량이급정학선택능구감소환자불량반응적발생。
Objective To investigate the causes and counter measures of ADR caused by Chinese medicine injection. Methods 245 ADR cases were chosen from 2012 to 2013.Literature metrology method was used for the collection and analysis of information in the medical record information. Results There were 148 cases of male patients (60.4%) and 97 cases of female patients (39.6%).Patients of 60 years old had the highest incidence (23.7 % ),while patients of 20 to 30 years old had the lowest incidence (8.2 % ).ADR was mainly happened in injections for clearing away heat and cardiovascular disease,while the Shuanghuanglian injection had the highest incidence (24 cases, 9.8%).The most common ADR were allergic reaction and skin reaction (56.3%). Conclusion Improving the quality and proper selection of Chinese medicine injection will reduce the occurrence of adverse reactions.