医学与哲学
醫學與哲學
의학여철학
MEDICINE AND PHILOSOPHY
2014年
18期
78-80,90
,共4页
脂肪干细胞%脂肪颗粒%血管化%生物支架
脂肪榦細胞%脂肪顆粒%血管化%生物支架
지방간세포%지방과립%혈관화%생물지가
adipose tissues derived stem cells%fat particles%neovascularization%cellular scaffold
本研究探讨脂肪干细胞复合脂肪颗粒对裸鼠皮下血管化的影响。将12只裸鼠身上标记三个点,将三组试剂分别注射,分析结果如下:肉眼观察:取材时,裸鼠背部注射部皮下有一团状组织块,脂肪组织形状不规则,大小不一。微血管密度:A组明显高于B组、C组,且差异有统计学意义(P<0.01);B组明显高于C组,且差异有统计学意义(P<0.01)。存活率比较:A组明显高于B组、C组,且差异有统计学意义(P<0.01);B组明显高于C组,且差异有统计学意义(P<0.01)。脂肪颗粒作为生物支架可加速脂肪干细胞的促血管化作用,从而促进移植物的存活与生长。
本研究探討脂肪榦細胞複閤脂肪顆粒對裸鼠皮下血管化的影響。將12隻裸鼠身上標記三箇點,將三組試劑分彆註射,分析結果如下:肉眼觀察:取材時,裸鼠揹部註射部皮下有一糰狀組織塊,脂肪組織形狀不規則,大小不一。微血管密度:A組明顯高于B組、C組,且差異有統計學意義(P<0.01);B組明顯高于C組,且差異有統計學意義(P<0.01)。存活率比較:A組明顯高于B組、C組,且差異有統計學意義(P<0.01);B組明顯高于C組,且差異有統計學意義(P<0.01)。脂肪顆粒作為生物支架可加速脂肪榦細胞的促血管化作用,從而促進移植物的存活與生長。
본연구탐토지방간세포복합지방과립대라서피하혈관화적영향。장12지라서신상표기삼개점,장삼조시제분별주사,분석결과여하:육안관찰:취재시,라서배부주사부피하유일단상조직괴,지방조직형상불규칙,대소불일。미혈관밀도:A조명현고우B조、C조,차차이유통계학의의(P<0.01);B조명현고우C조,차차이유통계학의의(P<0.01)。존활솔비교:A조명현고우B조、C조,차차이유통계학의의(P<0.01);B조명현고우C조,차차이유통계학의의(P<0.01)。지방과립작위생물지가가가속지방간세포적촉혈관화작용,종이촉진이식물적존활여생장。
This paper disscussed the effect of promoting neovascularization from adipose tissues derived stem cells combining with fat particles .The experimental animals were selected from the same 12 nude ,each nude muse was marked with 3 points and injected into the subcutaneous stratum of the 12 nude mice .Results as the follows :General observation ,When drawn ,we can see a group of tissue blocks in injected subcutaneously of nude mice ,the sizes and shapes of adipose tissue were irregular .Microvessel density ,group A was higher than group B and group C ,and had significant statistically differences (P< 0 .01) ,group B was higher than group C ,and had significant statistically differences (P< 0 .01) . Comparison of survival (% ) ,Group A was higher than group B and group C ,and had significant statistically differences (P<0 .01) ,group B was higher than group C ,and had significant statistically differences (P<0 .01) .As a cellular scaffold ,fat particles can accelerate the vascularization of ADSCs and promote thesurvial and growth of transplanted ADSCs .