医学与哲学
醫學與哲學
의학여철학
MEDICINE AND PHILOSOPHY
2014年
18期
37-39
,共3页
局部复发乳腺癌%远处转移乳腺癌%手术治疗%生存率%无进展生存期
跼部複髮乳腺癌%遠處轉移乳腺癌%手術治療%生存率%無進展生存期
국부복발유선암%원처전이유선암%수술치료%생존솔%무진전생존기
breast cancer with local recurrence%breast cancer with distant metastasis%surgical treatment%survival%progression-free survival
探索手术治疗单一局部复发或唯一远处转移病灶乳腺癌的临床价值。收集2006年6月至2013年6月湖南省人民医院乳甲外科收治的64例局部复发或术后远处转移乳腺癌患者，其中28例为单发病灶病例。根据是否采取了包含手术的综合治疗，将其分为手术组与非手术组。回顾性分析两组的临床资料和随访数据，分析手术治疗局部复发或远处转移乳腺癌有无临床意义。结果28例都采取了含化疗的综合治疗，8例局部单发病灶与9例远处单一脏器转移病例进行了手术治疗。手术组的局部缓解率与控制率明显优于非手术组，均为100％。两组无进展生存时间（PFS ）和总生存时间（OS ）比较，手术组明显长于非手术组；但在单一远处脏器转移手术组中OS没有优势。2年生存率方面手术组与非手术组比较有统计学意义。对于术后单一局部复发病灶或唯一远处脏器转移的乳腺癌患者，采取含手术的综合治疗方案能带来明显的PFS优势，若有手术机会和条件成熟，手术仍是不应放弃的有效治疗方法。
探索手術治療單一跼部複髮或唯一遠處轉移病竈乳腺癌的臨床價值。收集2006年6月至2013年6月湖南省人民醫院乳甲外科收治的64例跼部複髮或術後遠處轉移乳腺癌患者，其中28例為單髮病竈病例。根據是否採取瞭包含手術的綜閤治療，將其分為手術組與非手術組。迴顧性分析兩組的臨床資料和隨訪數據，分析手術治療跼部複髮或遠處轉移乳腺癌有無臨床意義。結果28例都採取瞭含化療的綜閤治療，8例跼部單髮病竈與9例遠處單一髒器轉移病例進行瞭手術治療。手術組的跼部緩解率與控製率明顯優于非手術組，均為100％。兩組無進展生存時間（PFS ）和總生存時間（OS ）比較，手術組明顯長于非手術組；但在單一遠處髒器轉移手術組中OS沒有優勢。2年生存率方麵手術組與非手術組比較有統計學意義。對于術後單一跼部複髮病竈或唯一遠處髒器轉移的乳腺癌患者，採取含手術的綜閤治療方案能帶來明顯的PFS優勢，若有手術機會和條件成熟，手術仍是不應放棄的有效治療方法。
탐색수술치료단일국부복발혹유일원처전이병조유선암적림상개치。수집2006년6월지2013년6월호남성인민의원유갑외과수치적64례국부복발혹술후원처전이유선암환자，기중28례위단발병조병례。근거시부채취료포함수술적종합치료，장기분위수술조여비수술조。회고성분석량조적림상자료화수방수거，분석수술치료국부복발혹원처전이유선암유무림상의의。결과28례도채취료함화료적종합치료，8례국부단발병조여9례원처단일장기전이병례진행료수술치료。수술조적국부완해솔여공제솔명현우우비수술조，균위100％。량조무진전생존시간（PFS ）화총생존시간（OS ）비교，수술조명현장우비수술조；단재단일원처장기전이수술조중OS몰유우세。2년생존솔방면수술조여비수술조비교유통계학의의。대우술후단일국부복발병조혹유일원처장기전이적유선암환자，채취함수술적종합치료방안능대래명현적PFS우세，약유수술궤회화조건성숙，수술잉시불응방기적유효치료방법。
To explore the clinical value of surgical treatment to a single local recurrence or distant metastasis of breast cancer .We collected 64 cases of breast cancer patients that have local recurrence or distant metastases from June 2006 to June 2013 in Hunan Provincial People's Hospital ,including 28 cases of single lesion cases .Depending on whether to take a comprehensive treatment includes surgery or not ,we divided the cases into surgical group or non-surgical group .A retrospective analysis of two sets of clinical data and follow-up data was collected to analysis the clinical value of the surgery to the patients with local recurrence and distant metastasis .28 cases have taken a comprehensive treatment with chemotherapy ,eight cases of partial single lesion and nine cases of a single distant metastasis have taken a surgery .Partial remission rate and control rate of surgical group were significantly better than that of the non-surgical group that both are 100% .Two PFS and OS were compared .Surgery group was significantly longer than non-surgical group ;however ,to OS ,there is no advantage in the surgical group that with a single distant metastasis .Compared the surgical group with non-surgical group ,2-year survival rate was statistically significant .For a breast cancer patient after surgery with single local recurrence or distant unique metastasis ,comprehensive treatment program including surgery can bring significant advantage of PFS .Surgery is still an effective treatment methods in certain conditions and doctors should never give up if there is opportunity for surgery and the conditions enough .
