医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2014年
26期
83-83
,共1页
妇科恶性肿瘤%良性肿瘤%血清肿瘤标志物%临床诊断
婦科噁性腫瘤%良性腫瘤%血清腫瘤標誌物%臨床診斷
부과악성종류%량성종류%혈청종류표지물%림상진단
Gynecological malignant tumor%Benign tumor%Serum tumor markers%Clinical diagnosis
目的探讨评价盆腔良、恶性妇科肿瘤诊断与鉴别诊断应用血清肿瘤标志物检测的临床意义。方法选取我院收治的50例妇科恶性肿瘤患者、85例良性肿瘤患者为研究对象,同时选取同期在我院行健康体检的90例健康正常女性作为对照,应用微粒子化学发光分别检测入选对象的糖类抗原(CA)125、153、199,甲胎蛋白(AFP)以及癌胚抗原(CEA)浓度,对比分析三组研究对象的检测结果。结果三组检测的AFP、CEA浓度水平并无明显差异(>0.05),良性肿瘤患者的CA125、CA153、CA199浓度水平均高于健康正常组,其中CA199浓度水平差异对比具有统计学意义(<0.05)；恶性肿瘤患者与良性肿瘤组、健康正常组相比,CA125、CA153、CA199浓度水平均明显升高(P<0.05)。CA125、CA199在盆腔良、恶性妇科肿瘤患者中的阳性检测率较高。结论 CA125、CA153、CA199三种血清肿瘤标志物联合检测,可为临床诊断与鉴别诊断盆腔良、恶性妇科肿瘤提供重要参考依据。
目的探討評價盆腔良、噁性婦科腫瘤診斷與鑒彆診斷應用血清腫瘤標誌物檢測的臨床意義。方法選取我院收治的50例婦科噁性腫瘤患者、85例良性腫瘤患者為研究對象,同時選取同期在我院行健康體檢的90例健康正常女性作為對照,應用微粒子化學髮光分彆檢測入選對象的糖類抗原(CA)125、153、199,甲胎蛋白(AFP)以及癌胚抗原(CEA)濃度,對比分析三組研究對象的檢測結果。結果三組檢測的AFP、CEA濃度水平併無明顯差異(>0.05),良性腫瘤患者的CA125、CA153、CA199濃度水平均高于健康正常組,其中CA199濃度水平差異對比具有統計學意義(<0.05)；噁性腫瘤患者與良性腫瘤組、健康正常組相比,CA125、CA153、CA199濃度水平均明顯升高(P<0.05)。CA125、CA199在盆腔良、噁性婦科腫瘤患者中的暘性檢測率較高。結論 CA125、CA153、CA199三種血清腫瘤標誌物聯閤檢測,可為臨床診斷與鑒彆診斷盆腔良、噁性婦科腫瘤提供重要參攷依據。
목적탐토평개분강량、악성부과종류진단여감별진단응용혈청종류표지물검측적림상의의。방법선취아원수치적50례부과악성종류환자、85례량성종류환자위연구대상,동시선취동기재아원행건강체검적90례건강정상녀성작위대조,응용미입자화학발광분별검측입선대상적당류항원(CA)125、153、199,갑태단백(AFP)이급암배항원(CEA)농도,대비분석삼조연구대상적검측결과。결과삼조검측적AFP、CEA농도수평병무명현차이(>0.05),량성종류환자적CA125、CA153、CA199농도수평균고우건강정상조,기중CA199농도수평차이대비구유통계학의의(<0.05)；악성종류환자여량성종류조、건강정상조상비,CA125、CA153、CA199농도수평균명현승고(P<0.05)。CA125、CA199재분강량、악성부과종류환자중적양성검측솔교고。결론 CA125、CA153、CA199삼충혈청종류표지물연합검측,가위림상진단여감별진단분강량、악성부과종류제공중요삼고의거。
Objective To study the evaluation of benign and malignant pelvic gynecologic tumor diagnosis and dif erential diagnosis of the clinical significance of the application of serum tumor markers detection. Methods Selection 50 patients with gynecological malignant tumor of our hospital, 85 cases of benign tumor patients as the research object,At the same time selection in the same period in our line of normal physical examination of 90 cases of healthy women as control,Application of micro particle chemiluminescence detection respectively selected objects of carbohydrate antigen (CA) 125, 153, 199, a tire protein (AFP) and carcinoembryonic antigen (CEA) concentration, contrast analysis of test results of three groups of subjects.Results The three groups of detection of AFP, CEA levels and no significant dif erence ( >0.05), patients with benign tumor of CA125, CA153, CA199 levels were higher than in healthy normal group,Among CA199 levels compared statistical y significant dif erence ( <0.05);Malignant tumor patients compared with benign tumor and healthy normal group, CA125, CA153, CA199 levels were significantly higher ( <0.05). CA125 and CA199 in patients with benign and malignant gynecological pelvic tumors in the positive detection rate is higher. Conclusion CA125, CA153, CA199, three kinds of joint detection of serum tumor markers for clinical diagnosis and dif erential diagnosis of benign and malignant pelvic tumors of department of gynaecology to provide important reference basis.
