CAJ | 학술논문

目的探讨开颅手术后并发细菌性脑膜炎的危险因素和治疗措施。方法回顾性分析2008年10月~2013年10月开颅手术后发生细菌性脑膜炎患者的临床资料。结果术后细菌性脑膜炎的发生率为3.6%，年龄大于50岁、手术时间大于4H、幕下部位手术、术后引流管留置超过3d、合并脑脊液漏以及开放性颅脑损伤患者均较平均感染率明显升高(P<0.05)。结论年龄、手术时间、手术部位、引流管留置时间、脑脊液漏、开放性颅脑损伤是开颅术后并发细菌性脑膜炎的相关危险因素。避免脑脊液漏及长期留置颅内引流管，尽早联合使用敏感抗生素可取得良好的治疗效果。
목적탐토개로수술후병발세균성뇌막염적위험인소화치료조시。방법회고성분석2008년10월~2013년10월개로수술후발생세균성뇌막염환자적림상자료。결과술후세균성뇌막염적발생솔위3.6%，년령대우50세、수술시간대우4H、막하부위수술、술후인류관류치초과3d、합병뇌척액루이급개방성로뇌손상환자균교평균감염솔명현승고(P<0.05)。결론년령、수술시간、수술부위、인류관류치시간、뇌척액루、개방성로뇌손상시개로술후병발세균성뇌막염적상관위험인소。피면뇌척액루급장기류치로내인류관，진조연합사용민감항생소가취득량호적치료효과。
Objective To investigate the risk factors and treatment of bacterial meningitis after craniotomy. Methods Clinical data of patients suf ered from postoperative bacterial meningitis between October 2008 and October 2013 were analyzed retrospectively. Results The incidence of bacterial meningitis was 3.6%. The infectious rate enhanced significantly in Elder patients (>50 year old), longer duration of operation group, and patients who underwent infratentorial craniotomy, prolonged drainage, cerebrospinofluid leakage and open craniocerebral injury ( <0.05). Conclusion The risk factors of bacterial meningitis after craniotomy include age, duration of operation and postoperative drainage, operative site, CSF leakage and open brain injury. Avoiding CSF leakage and using antibiotics based on bacterial-sensitive test as early as possible can improve curative effect.