CAJ | 학술논문

诱导性多能干细胞（iPSCs）是人类和动物的体细胞通过转导特定转录因子重编程序而获得与胚胎干细胞（ESC）相似的多潜能干细胞。iPSCs细胞具有无限增殖，自我更新，多向分化的特点。本文主要总结 iPSCs在心血管领域的研究现状，应用价值及前景，以及 iPSCs现阶段应用的缺陷。
유도성다능간세포（iPSCs）시인류화동물적체세포통과전도특정전록인자중편정서이획득여배태간세포（ESC）상사적다잠능간세포。iPSCs세포구유무한증식，자아경신，다향분화적특점。본문주요총결 iPSCs재심혈관영역적연구현상，응용개치급전경，이급 iPSCs현계단응용적결함。
Induced pluripotent stem cells (iPSCs)are pluripotent stem cells obtained through transduction of specific transcription factors and reprogramming of human and animal somatic cells,Which are similar to embryonic stem cells.The iPSCs possesses characteristics of unlimited proliferation,self-reneWal and multi-differentiation.This arti-cle mainly summarized current research condition,application value and prospects of iPSCs in cardiovascular area, and its defect in application of current stage.