CAJ | 학술논문

目的：研究不同型号活检针对肾活检成功率及并发症的影响。方法将486例患者分成两组，16G组216例患者采用16 G Cru- cut手动活检针进行彩超引导下肾组织活检；18G组270例患者采用18 G Cru- cut活检针。16G活检针穿刺要求取材2条肾组织，18G活检针穿刺要求取材3条肾组织。结果两组活检总成功率94.44%。16G组活检成功率93.52%；平均穿刺次数（2.57±0.34）次；并发症发生率8.80%（肉眼血尿5.56%，肾包膜下血肿3.24%）。18G组活检成功率95.19%；平均穿刺次数（2.84±0.51）次；并发症发生率5.56%（肉眼血尿4.07%，肾包膜下血肿1.48%），两组成功率、并发症发生率均无统计学差异（均P＞0.05），两组穿刺次数有统计学差异（P＜0.01）。16G组光镜下平均肾小球数量（19.33±4.91）个；18G组光镜下平均肾小球数量（25.27±6.23）个；两组比较有统计学差异（P＜0.05）。结论使用18G针进行超声引导下肾活检，虽多取材1次，但与16G针比较不增加并发症。两种活检针取材的有效肾小球数量有差异，但均可保证光镜、电镜及免疫荧光检测的标本质量。
목적：연구불동형호활검침대신활검성공솔급병발증적영향。방법장486례환자분성량조，16G조216례환자채용16 G Cru- cut수동활검침진행채초인도하신조직활검；18G조270례환자채용18 G Cru- cut활검침。16G활검침천자요구취재2조신조직，18G활검침천자요구취재3조신조직。결과량조활검총성공솔94.44%。16G조활검성공솔93.52%；평균천자차수（2.57±0.34）차；병발증발생솔8.80%（육안혈뇨5.56%，신포막하혈종3.24%）。18G조활검성공솔95.19%；평균천자차수（2.84±0.51）차；병발증발생솔5.56%（육안혈뇨4.07%，신포막하혈종1.48%），량조성공솔、병발증발생솔균무통계학차이（균P＞0.05），량조천자차수유통계학차이（P＜0.01）。16G조광경하평균신소구수량（19.33±4.91）개；18G조광경하평균신소구수량（25.27±6.23）개；량조비교유통계학차이（P＜0.05）。결론사용18G침진행초성인도하신활검，수다취재1차，단여16G침비교불증가병발증。량충활검침취재적유효신소구수량유차이，단균가보증광경、전경급면역형광검측적표본질량。
Objective To compare the use of 16G and 18G biopsy needles in percutaneous ultrasound- guided renal biopsy. Methods Four hundred and eighty six patients undergoing percutaneous ultrasound- guided renal biopsy were as-signed to use 16G Cru- cut biopsy needle (n=216) or 18G needle (n=270). Two specimens of renal tissue were required to be taken for 16G group and 3 specimens were required for 18G group. Results The overal success rate of biopsy was 94.4%, that was 93.6%in 16G group and 95.2%in 18G group (P>0.05). The average biopsy times in 16G group was 2.57±0.34 and that in 18G group was 2.84±0.51(P<0.01). The complication rate in G16 group was 8.80%(gross hematuria 5.56%, subcapsular renal hematoma 3.24%) and that in G18 group was 5.56%(gross hematuria 4.07%, subcapsular renal hematoma 1.48%) (P>0.05). The average number of glomerulum under light microscope in 16G group was 19.33 ±4.91and that in 18G group was 25.27±6.23 (P<0.05). Conclusion Ultrasound- guided renal biopsies using 18G Cru- cut biopsy needle does not increase the incidence of complications, although one more specimen need to be taken compared to using 16G. The specimens of renal tis-sue taken using both needles meet standard of light, immunofluorescence and electron microscopic examinations.