CAJ | 학술논문

采用LiCl/DMAc的溶解体系将细菌纤维素溶解后制备再生细菌纤维素(RBC)膜,并研究了成膜的细菌纤维素溶液浓度对膜的结晶度、平衡含水率、透光率以及对营养物质(氯化钠、葡萄糖、色氨酸)的透过性能的影响.实验结果表明,随着成膜溶液浓度的升高,再生膜的结晶度有一定程度的降低；平衡含水率稍有升高；再生膜干态下的透光率变化不大,但浸泡PBS后膜变化较大；对营养物质的透过系数随浓度变化较小,对葡萄糖和色氨酸的透过系数相近,约为1．0×10-6 cm2/s,氯化钠的透过率系数约为2．5×10-6 cm2/s.研究表明再生细菌纤维素膜是一种潜在的人工角膜板层移植材料.
채용LiCl/DMAc적용해체계장세균섬유소용해후제비재생세균섬유소(RBC)막,병연구료성막적세균섬유소용액농도대막적결정도、평형함수솔、투광솔이급대영양물질(록화납、포도당、색안산)적투과성능적영향.실험결과표명,수착성막용액농도적승고,재생막적결정도유일정정도적강저；평형함수솔초유승고；재생막간태하적투광솔변화불대,단침포PBS후막변화교대；대영양물질적투과계수수농도변화교소,대포도당화색안산적투과계수상근,약위1．0×10-6 cm2/s,록화납적투과솔계수약위2．5×10-6 cm2/s.연구표명재생세균섬유소막시일충잠재적인공각막판층이식재료.
In this work,regenerated bacterial cellulose (RBC)membrane was prepared by LiCl/DMAc,and in-fluence of the concentration of bacterial cellulose solution on crystallinity,equilibrium water content,light transmittance and the diffusion of nutrients (sodium chloride,glucose sugar,tryptophan)of RBC membrane were studied.The experimental results showed that,with the concentration of bacterial cellulose solution in-creasing,the degree of crystallinity of regenerated membrane slightly decreased;equilibrium water content in-creased slightly and light transmittance of dry films changed little,but that of wet films changed obviously;the diffusion coefficient to nutrients hardly changed with the BC solution concentration,and that to glucose sugar and tryptophan were approximately 1.0 × 10-6 cm2/s,and the sodium chloride permeability coefficient was about 2.5×10-6 cm2/s.This work indicated that RBC membrane was promising biomaterial for corneal lamellar transplantation application.