中国药师
中國藥師
중국약사
CHINA PHARMACIST
2014年
5期
857-859
,共3页
奥硝唑%滴虫性阴道炎%疗效%安全性
奧硝唑%滴蟲性陰道炎%療效%安全性
오초서%적충성음도염%료효%안전성
Ornidazole%Trichomonal vaginitis%Curative effect%Safety
目的：探讨奥硝唑治疗滴虫性阴道炎患者的疗效及安全性。方法：112例滴虫性阴道炎患者随机分为观察组和对照组各56例。对照组予甲硝唑片200 mg,po, tid,观察组予奥硝唑片500 mg, po, tid,治疗5 d。比较两组患者临床疗效、疗状体征评分后不良反应。结果：观察组总有效率为96.4%,高于对照组82.1%(P<0.05)；治疗后,两组患者各症状评分均较治疗前明显改善(P<0.05),两组治疗后症状体征评分比较差异无统计学意义(P>0.05)；观察组不良反应发生率明显低于对照组(P<0.05)。结论：奥硝唑治疗滴虫性阴道炎临床疗效显著,且药物不良反应发生率低,患者耐受性好,值得临床推广。
目的：探討奧硝唑治療滴蟲性陰道炎患者的療效及安全性。方法：112例滴蟲性陰道炎患者隨機分為觀察組和對照組各56例。對照組予甲硝唑片200 mg,po, tid,觀察組予奧硝唑片500 mg, po, tid,治療5 d。比較兩組患者臨床療效、療狀體徵評分後不良反應。結果：觀察組總有效率為96.4%,高于對照組82.1%(P<0.05)；治療後,兩組患者各癥狀評分均較治療前明顯改善(P<0.05),兩組治療後癥狀體徵評分比較差異無統計學意義(P>0.05)；觀察組不良反應髮生率明顯低于對照組(P<0.05)。結論：奧硝唑治療滴蟲性陰道炎臨床療效顯著,且藥物不良反應髮生率低,患者耐受性好,值得臨床推廣。
목적：탐토오초서치료적충성음도염환자적료효급안전성。방법：112례적충성음도염환자수궤분위관찰조화대조조각56례。대조조여갑초서편200 mg,po, tid,관찰조여오초서편500 mg, po, tid,치료5 d。비교량조환자림상료효、료상체정평분후불량반응。결과：관찰조총유효솔위96.4%,고우대조조82.1%(P<0.05)；치료후,량조환자각증상평분균교치료전명현개선(P<0.05),량조치료후증상체정평분비교차이무통계학의의(P>0.05)；관찰조불량반응발생솔명현저우대조조(P<0.05)。결론：오초서치료적충성음도염림상료효현저,차약물불량반응발생솔저,환자내수성호,치득림상추엄。
Objective:To explore the efficacy and safety of ornidazole in the treatment of trichomonal vaginitis. Methods:Totally 112 cases of trichomonal vaginitis from February 2011 to December 2012 in our hospital were selected and randomly divided into the ob-servation group and the control group with 56 cases in each. The control group was treated with metronidazole tablets 200mg, po,tid, and the observation group was treated with ornidazole tablets 500mg, po,bid. The treatment course was 7 days. The clinical effect, score of clinical symptoms and incidence of adverse reactions of the two groups were compared. Results:The total effective rate of the observation group was 96. 4%, which was higher than that of the control group (82. 1%), and the difference was statistically signifi-cant (P<0. 05). The symptom scores of the two groups were significantly improved after the treatment (P<0. 05), however, the score between the two groups showed no significant difference (P>0. 05). The incidence rate of adverse reactions in the observation group was 10. 71%, which was significantly lower than that in the control group (37. 5%), and the difference was statistically signifi-cant (P<0. 05). Conclusion:The clinical curative effect of ornidazole in the treatment of trichomonal vaginitis is notable with faster onset, shorter treatment course, lower adverse reaction rate and better patient tolerance,which is valuable in the clinical promotion.
