医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2013年
27期
94-94
,共1页
肌酸激酶MB同工酶%肌酸激酶%生化检测%化学发光%方法学设计
肌痠激酶MB同工酶%肌痠激酶%生化檢測%化學髮光%方法學設計
기산격매MB동공매%기산격매%생화검측%화학발광%방법학설계
CKMB%CK%Biochemical detection%Chemiluminescence%Methods study design
目的：探讨生化检测中肌酸激酶MB型同工酶结果高于肌酸激酶结果的原因。方法对82例肌酸激酶（CK）结果正常，但肌酸激酶MB型同工酶（CKMB）结果高于肌酸激酶（CK）结果的标本，分别在化学发光上进行CKMB检测。同时选取20例健康体检者作为对照标本。结果82例标本在生化分析仪上测得的 CKMB结果明显高于对照组结果，差异显著（P＜0.01）,有统计学意义；而在化学发光上测得的CKMB结果与健康对照组相比无显著差异（P＞0.05）,无统计学意义。结论生化检测中出现的CKMB结果高于CK结果的情况应该是试剂方法学所致，CKMB试剂在设计时没有考虑到一些病理情况下机体情况的变化。
目的：探討生化檢測中肌痠激酶MB型同工酶結果高于肌痠激酶結果的原因。方法對82例肌痠激酶（CK）結果正常，但肌痠激酶MB型同工酶（CKMB）結果高于肌痠激酶（CK）結果的標本，分彆在化學髮光上進行CKMB檢測。同時選取20例健康體檢者作為對照標本。結果82例標本在生化分析儀上測得的 CKMB結果明顯高于對照組結果，差異顯著（P＜0.01）,有統計學意義；而在化學髮光上測得的CKMB結果與健康對照組相比無顯著差異（P＞0.05）,無統計學意義。結論生化檢測中齣現的CKMB結果高于CK結果的情況應該是試劑方法學所緻，CKMB試劑在設計時沒有攷慮到一些病理情況下機體情況的變化。
목적：탐토생화검측중기산격매MB형동공매결과고우기산격매결과적원인。방법대82례기산격매（CK）결과정상，단기산격매MB형동공매（CKMB）결과고우기산격매（CK）결과적표본，분별재화학발광상진행CKMB검측。동시선취20례건강체검자작위대조표본。결과82례표본재생화분석의상측득적 CKMB결과명현고우대조조결과，차이현저（P＜0.01）,유통계학의의；이재화학발광상측득적CKMB결과여건강대조조상비무현저차이（P＞0.05）,무통계학의의。결론생화검측중출현적CKMB결과고우CK결과적정황응해시시제방법학소치，CKMB시제재설계시몰유고필도일사병리정황하궤체정황적변화。
Objective To explore result of CKMB higher than CK in biochemical tests. Methods In82 cases of CK were normal, but the CKMB results were higher than CK by using biochemical analyzer, and CKMB were detected in the chemiluminescence respectively. While 20 healthy subjects served as control specimens. Results 82 cases of specimens in biochemical analyzer measured the result of CKMB were higher than those in the control group, significant dif erence (P<0.01), there is statistical significance;and the chemiluminescence on the measured CKMB results compared with health control group had no significant dif erence (P>0.05) , no statistical significance. Conclusion Biochemical detection in CKMB were higher than CK results is caused by CKMB reagent method. Reagent in the design not consider the body changes in pathological situations.
