CAJ | 학술논문

目的：探讨甲基强的松龙联合硫酸镁治疗重症支气管哮喘的临床疗效。方法将我院2010年1月至2013年7月间收治的104例重症支气管哮喘患者按照数字随机法分为观察组和对照组，每组各52例，对照组患者给予甲基强的松龙治疗，观察组患者给予甲基强的松龙联合硫酸镁治疗，比较两组患者的临床疗效及治疗后的肺功能指标。结果观察组患者的治疗总有效率为92.3%，显著优于对照组患者的76.9%，组间差异有统计学意义（P＜0.05）。观察组患者治疗后的FVC及PEF水平较治疗组患者有显著改善，组间差异有统计学意义（P＜0.05）。结论采用甲基强的松龙联合硫酸镁治疗重症支气管哮喘临床疗效好，对于控制哮喘症状，改善患者的肺功能具有重要的意义。
목적：탐토갑기강적송룡연합류산미치료중증지기관효천적림상료효。방법장아원2010년1월지2013년7월간수치적104례중증지기관효천환자안조수자수궤법분위관찰조화대조조，매조각52례，대조조환자급여갑기강적송룡치료，관찰조환자급여갑기강적송룡연합류산미치료，비교량조환자적림상료효급치료후적폐공능지표。결과관찰조환자적치료총유효솔위92.3%，현저우우대조조환자적76.9%，조간차이유통계학의의（P＜0.05）。관찰조환자치료후적FVC급PEF수평교치료조환자유현저개선，조간차이유통계학의의（P＜0.05）。결론채용갑기강적송룡연합류산미치료중증지기관효천림상료효호，대우공제효천증상，개선환자적폐공능구유중요적의의。
Objective To investigate the clinical efifcacy of methylprednisolone combined with magnesium sulfate and severe bronchial asthma treatment of methylprednisolone. Methods 104 cases of severe bronchial asthma patients admitted in our hospital in 2010 January~2013 July according to randomly divided into observation group and control group, 52 cases in each group, the control with patients in the treatment group were given methyl prednisone, prednisolone combined with magnesium sulfate in the treatment of observation group were treated with methylprednisolone, compare the clinical curative effect and treatment two groups of patients after lung function index. Results In the treatment group the total effective rate was 92.3%, signiifcantly better than the control group of 76.9%patients, there was signiifcant difference between the groups (P<0.05). Observation of FVC and PEF levels after treatment in patients group than the patients in the treatment group were improved signiifcantly, there was signiifcant difference between the groups (P<0.05).Conclusion Me thylprednisolone combined with magnesium sulfate in the treatment of severe bronchial asthma clinical efifcacy of methylprednisolone, for control of asthma symptoms, has important signiifcance to improve the pulmonary function in patients with.