中国实用医药
中國實用醫藥
중국실용의약
CHINA PRACTICAL MEDICAL
2013年
33期
33-34
,共2页
糖尿病肾病%联合治疗%临床疗效
糖尿病腎病%聯閤治療%臨床療效
당뇨병신병%연합치료%림상료효
Diabetes nephropathy%Combined treatment%Clinical effect
目的：观察前列地尔联合缬沙坦治疗早期糖尿病肾病的临床疗效。方法从本院2011年1月~2013年1月内分泌科收治的糖尿病肾病患者中选取60例，其中30例给予前列地尔联合缬沙坦治疗，标记为实验组；30例仅给予前列地尔治疗，标记为对照组，均为4周/疗程。结果治疗2疗程后实验组显效18例，无效6例，总有效率80%；对照组显效12例，无效10例，总有效率66.7%。差异具有统计学意义(P<0.05)；实验组副作用较对照组少，差异无统计学意义(P>0.05)。结论应用前列地尔联合缬沙坦治疗早期糖尿病肾病疗效显著，无明显不良反应，值得临床大力推广。
目的：觀察前列地爾聯閤纈沙坦治療早期糖尿病腎病的臨床療效。方法從本院2011年1月~2013年1月內分泌科收治的糖尿病腎病患者中選取60例，其中30例給予前列地爾聯閤纈沙坦治療，標記為實驗組；30例僅給予前列地爾治療，標記為對照組，均為4週/療程。結果治療2療程後實驗組顯效18例，無效6例，總有效率80%；對照組顯效12例，無效10例，總有效率66.7%。差異具有統計學意義(P<0.05)；實驗組副作用較對照組少，差異無統計學意義(P>0.05)。結論應用前列地爾聯閤纈沙坦治療早期糖尿病腎病療效顯著，無明顯不良反應，值得臨床大力推廣。
목적：관찰전렬지이연합힐사탄치료조기당뇨병신병적림상료효。방법종본원2011년1월~2013년1월내분비과수치적당뇨병신병환자중선취60례，기중30례급여전렬지이연합힐사탄치료，표기위실험조；30례부급여전렬지이치료，표기위대조조，균위4주/료정。결과치료2료정후실험조현효18례，무효6례，총유효솔80%；대조조현효12례，무효10례，총유효솔66.7%。차이구유통계학의의(P<0.05)；실험조부작용교대조조소，차이무통계학의의(P>0.05)。결론응용전렬지이연합힐사탄치료조기당뇨병신병료효현저，무명현불량반응，치득림상대력추엄。
Objective To observe the clinical effect of alprostadil combined valsartan for treatment of early-stage diabetes nephropathy. Methods 60 patients with diabetes nephropathy accepted by our endocrinology department were chosen. 30 cases were given alprostadil combined valsartan for treatment and marked as experiment group while 30 cases were given alprostadil tablets for treatment and marked as control group. 4 weeks set as one treatment course. Result After 2 treatment courses, total effective rate of experiment group was 80%(excellent 18 cases, noneffective 6 cases) and control group was 66.7%(excellent 12 cases, noneffective 10 cases), P<0.05. Side effects of experiment group were less than control group, P>0.05. Conclusion Alprostadil combined valsartan for treatment of early-stage diabetes nephropathy has an obvious effect and no serious side effects, so it's worth of being popularized in clinical work.
