CAJ | 학술논문

目的：探讨脑心通胶囊联合阿托伐他汀对脑梗死颈动脉粥样硬化患者的治疗效果。方法：以本院2010年1月-2013年1月间收治的脑梗死合并有颈动脉粥样硬化患者150例为研究对象，按照随机数字表法将其分为观察组和对照组各75例。对照组使用阿司匹林、阿托伐他汀钙片，观察组在此基础上增加使用脑心通胶囊，比较两组患者治疗后体内脂类代谢情况、粥样硬化情况和同型半胱氨酸水平。结果：观察组总胆固醇、血清甘油三酯和低密度脂蛋白胆固醇含量低于对照组，颈动脉内膜-中层厚度、斑块面积和Hcy含量小于对照组，两组比较差异均有统计学意义（P<0.05）。结论：使用脑心通胶囊联合阿托伐他汀治疗方案可以提高脑梗死合并颈动脉粥样硬化患者临床治疗效果，降低脑梗死复发危险和粥样硬化程度。
목적：탐토뇌심통효낭연합아탁벌타정대뇌경사경동맥죽양경화환자적치료효과。방법：이본원2010년1월-2013년1월간수치적뇌경사합병유경동맥죽양경화환자150례위연구대상，안조수궤수자표법장기분위관찰조화대조조각75례。대조조사용아사필림、아탁벌타정개편，관찰조재차기출상증가사용뇌심통효낭，비교량조환자치료후체내지류대사정황、죽양경화정황화동형반광안산수평。결과：관찰조총담고순、혈청감유삼지화저밀도지단백담고순함량저우대조조，경동맥내막-중층후도、반괴면적화Hcy함량소우대조조，량조비교차이균유통계학의의（P<0.05）。결론：사용뇌심통효낭연합아탁벌타정치료방안가이제고뇌경사합병경동맥죽양경화환자림상치료효과，강저뇌경사복발위험화죽양경화정도。
Objective:To investigate the effect of combined application of Naoxintong capsule and atorvastatin in the treatment of cerebral infarction with carotid artery atherosclerosis.Method:One hundred and fifty patients with cerebral infarction and carotid artery atherosclerosis were divided into the objective group and the control group,each group of 75 cases. The aspirin and atorvastatin were used in the control group and the Naoxintong capsule was added in the objective group. The lipid metabolism and the level of atherosclerosis and Hcy were compared between the two groups.Result:TC,TG,LDL-C,IMT,plaque area and the level of Hcy after the treatment of the objective group were lower than those of the control group,and HDL-C of the objective group was higher than the ones of the control group,and the difference between the two groups were statistically significant(P<0.05). Conclusion:It can get a satisfaction effect for combined application of Naoxintong capsule and atorvastatin in the treatment of cerebral infarction with carotid artery atherosclerosis.