中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
14期
2117-2118
,共2页
耳鼻喉外科手术%抗真菌药%鼻窦炎
耳鼻喉外科手術%抗真菌藥%鼻竇炎
이비후외과수술%항진균약%비두염
Otorhinolaryngologic surgical procedures%Antifungal agents%Sinusitis
目的 观察鼻内镜低温等离子辅助下鼻窦手术联合抗真菌药物对真菌性鼻-鼻窦炎的临床治疗效果.方法 回顾性分析108例真菌性鼻-鼻窦炎患者的临床资料,所有患者采用鼻内镜低温等离子辅助下鼻窦手术治疗.根据术后抗真菌药物使用与否分为观察组和对照组,观察组56例,术后应用氟康唑等抗真菌药物；对照组52例,术后采用0.9％氯化钠溶液清洗.对两组患者进行6个月至2年的随访,比较两组治疗效果和复发情况.结果 观察组56例患者,治愈49例,好转7例,无复发病例.对照组52例,治愈47例,好转4例,无效1例,复发3例.观察组复发率明显低于对照组,差异有统计学意义(x2 =4.82,P＜0.05).结论 鼻内镜低温等离子辅助下鼻窦手术联合抗真菌药物治疗真菌性鼻-鼻窦炎疗效确切,在预防和降低复发率上效果显著,可进行临床推广.
目的 觀察鼻內鏡低溫等離子輔助下鼻竇手術聯閤抗真菌藥物對真菌性鼻-鼻竇炎的臨床治療效果.方法 迴顧性分析108例真菌性鼻-鼻竇炎患者的臨床資料,所有患者採用鼻內鏡低溫等離子輔助下鼻竇手術治療.根據術後抗真菌藥物使用與否分為觀察組和對照組,觀察組56例,術後應用氟康唑等抗真菌藥物；對照組52例,術後採用0.9％氯化鈉溶液清洗.對兩組患者進行6箇月至2年的隨訪,比較兩組治療效果和複髮情況.結果 觀察組56例患者,治愈49例,好轉7例,無複髮病例.對照組52例,治愈47例,好轉4例,無效1例,複髮3例.觀察組複髮率明顯低于對照組,差異有統計學意義(x2 =4.82,P＜0.05).結論 鼻內鏡低溫等離子輔助下鼻竇手術聯閤抗真菌藥物治療真菌性鼻-鼻竇炎療效確切,在預防和降低複髮率上效果顯著,可進行臨床推廣.
목적 관찰비내경저온등리자보조하비두수술연합항진균약물대진균성비-비두염적림상치료효과.방법 회고성분석108례진균성비-비두염환자적림상자료,소유환자채용비내경저온등리자보조하비두수술치료.근거술후항진균약물사용여부분위관찰조화대조조,관찰조56례,술후응용불강서등항진균약물；대조조52례,술후채용0.9％록화납용액청세.대량조환자진행6개월지2년적수방,비교량조치료효과화복발정황.결과 관찰조56례환자,치유49례,호전7례,무복발병례.대조조52례,치유47례,호전4례,무효1례,복발3례.관찰조복발솔명현저우대조조,차이유통계학의의(x2 =4.82,P＜0.05).결론 비내경저온등리자보조하비두수술연합항진균약물치료진균성비-비두염료효학절,재예방화강저복발솔상효과현저,가진행림상추엄.
Objective To study the clinical effect of surgery combined with antifungal drug in treatment of fungal nose-sinusitis.Methods The clinical data of 108 cases with fungal nose-sinusitis were retrospectively analyzed.All patients were treated with nasal endoscopic sinus surgery.According to whether the patients received antifungal drugs after low-temperature plasma-assisted surgery,the patients were divided into the treatment group and the control group.The treatment group(56 cases) was given antifungal fluconazole after low-temperature plasma-assisted endoscopic sinus surgery.52 cases in the control group were washed by 0.9％ sodium chloride solution after conventional endoscopic sinus surgery.The patients were followed up for 6 months to 2 years,the therapeutic effect and recurrence were compared between the two groups.Results 56 patients of the treatment group,49 cases were cured,7 cases improved,no recurrence.52 cases in the control group,47 cases were cured,improved in 4 cases,ineffective in 1 case,3 cases of recurrence.The recurrence rate of the treatment group was significantly lower than the control group (x2 =4.82,P ＜ 0.05).Conclusion The low-temperature plasma-assisted surgery combined with antifungal drug.in the treatment of fungal nose-sinusitis has exact efficacy,and has significant effect on the prevention and reduce the relapse rate,which worthy of clinical promotion.
