CAJ | 학술논문

目的：研究趾肱指数（ TBI）在诊断2型糖尿病患者下肢动脉病变中临床意义与影响因素。方法采用多普勒血流探测仪检测2型糖尿病患者足趾动脉与肱动脉血压的比值，以TBI≤0.7为切割点分成低TBI组与正常TBI组，并分析比较两组临床及代谢参数。结果238例2型糖尿病患者中TBI≤0.7的32例，占总例数13.4％。低TBI组与正常TBI组比较，其年龄更高，舒张压更低，高血压、冠心病、脑血管病合并率增高；逐步回归分析显示，年龄、舒张压是TBI独立影响因素。结论TBI在诊断2型糖尿病下肢动脉病变中具有重要意义；低TBI患者有更高的心脑血管患病率；高龄、舒张压低是TBI的主要危险因素。
목적：연구지굉지수（ TBI）재진단2형당뇨병환자하지동맥병변중림상의의여영향인소。방법채용다보륵혈류탐측의검측2형당뇨병환자족지동맥여굉동맥혈압적비치，이TBI≤0.7위절할점분성저TBI조여정상TBI조，병분석비교량조림상급대사삼수。결과238례2형당뇨병환자중TBI≤0.7적32례，점총례수13.4％。저TBI조여정상TBI조비교，기년령경고，서장압경저，고혈압、관심병、뇌혈관병합병솔증고；축보회귀분석현시，년령、서장압시TBI독립영향인소。결론TBI재진단2형당뇨병하지동맥병변중구유중요의의；저TBI환자유경고적심뇌혈관환병솔；고령、서장압저시TBI적주요위험인소。
Objective To investigate toe-brachial index ( TBI) in the diagnosis of peripheral artery disease ( PAD) and its risk factors in the patients with type 2 diabetes.Methods TBI was examined in the 238 patients with type 2 diabetes.The patients were divided into the group with low TBI ( TBI≤0.7 ) and the group with normal ABI ( TBI>0.7 ) .The two groups were compared for clinical parameters.Results Thirty two patients (13.4%)with abnormal ABI (TBI≤0.7) showed older age [(63.8 ±9.9) yrs vs (54.9 ±10.8) yrs, P =0.000] , lower diastolic blood pressure [(70.5 ±6.9) mmHg vs (74.9 ±9.1) mmHg, P =0.003], more frequency of hypertension (56.3%vs 38.3%, P =0.043), coronary artery heart disease (28.7%vs 10.7%, P =0.020) and cere-bral vascular disease (15.6%vs 4.4%, P =0.025).Step-wise analysis screened that age and diastolic blood pressure were the inde-pendent risk factors for TBI .Conclusions Aging and hypertension were the risk factors in the patients with abnormal TBI in type 2 di-abetes.TBI was an easy and economical method for diagnosing PAD in patients with type 2 diabetes.