CAJ | 학술논문

目的：分析重症急性胰腺炎患者胰腺及胰周坏死的危险因素，探讨防治措施，为临床工作提供帮助。方法：对120例重症急性胰腺炎患者采取治疗后观察患者发生感染的情况，进而对并发胰腺感染的危险因素进行分析。结果：120例重症急性胰腺炎患者中并发胰腺感染者51例，感染率为42.50%，其发生率与患者低氧血症、血淀粉酶、血钙、机械通气、APACHEⅡ评分、糖尿病史等方面有统计学意义(P＜0.05)；患者胰腺坏死组织和腹水经病原菌培养得到85株病原菌，构成比前3位的病原菌分别为阴沟肠杆菌、铜绿假单胞菌和金黄色葡萄球菌。结论：低氧血症、机械通气、APACHEⅡ评分、糖尿病史是重症急性胰腺炎患者并发胰腺感染的危险因素。
목적：분석중증급성이선염환자이선급이주배사적위험인소，탐토방치조시，위림상공작제공방조。방법：대120례중증급성이선염환자채취치료후관찰환자발생감염적정황，진이대병발이선감염적위험인소진행분석。결과：120례중증급성이선염환자중병발이선감염자51례，감염솔위42.50%，기발생솔여환자저양혈증、혈정분매、혈개、궤계통기、APACHEⅡ평분、당뇨병사등방면유통계학의의(P＜0.05)；환자이선배사조직화복수경병원균배양득도85주병원균，구성비전3위적병원균분별위음구장간균、동록가단포균화금황색포도구균。결론：저양혈증、궤계통기、APACHEⅡ평분、당뇨병사시중증급성이선염환자병발이선감염적위험인소。
Objective To analyze the risk factors of pancreatic infections in patients with severe acute pan-creatitis(SAP) and investigate the prevention and control measures of clinical treatment. Methods One hun-dred and twenty patients with SAP received active treatment after taking prevention measures,and the risk fac-tors for the concurrent pancreatic infections were analyzed. Results Of all 120 patients with SAP investigat-ed,the pancreatic infections occurred in 51 patients with the incidence rate of 42.50%. There was statistically significance between the incidence of pancreatic infections and hypoxemia,serum amylase,serum calcium,me-chanical ventilation,APACHEⅡ score and diabetes history (P<0.05). All 85 strains of microorganisms were cultured from necrotic pancreatic tissue or ascites,among which the top three species were Enterobacter cloacae, Pseudomonas aeruginosa and Staphylococcus aureus. Conclusion The hypoxemia,fasting time,mechanical ventilation,APACHE II score,diabetes history are the risk factors leading to pancreatic infections in patients with SAP.