CAJ | 학술논문

背景糖尿病可影响人体内多个系统不同器官的功能,从而严重威胁人类健康.糖尿病神经病变(diabetic neuropathy,DN)是糖尿病最常见的慢性并发症之一,病变可累及中枢神经及周围神经,给患者带来不同程度的痛苦,严重的甚至致残,使患者丧失正常生活能力. 目的为更好地认识痛性糖尿病神经病变(painful diabetic neuropathy,PDN)的危害,并在临床上采取早期预防及有效治疗的方法,特作一综述. 内容综合相关文献,归纳分析糖尿病引发PDN的发病机制、临床表现、诊断与治疗的最新进展. 趋向该并发症得到更广泛关注和深入的认识.
배경 당뇨병가영향인체내다개계통불동기관적공능,종이엄중위협인류건강.당뇨병신경병변(diabetic neuropathy,DN)시당뇨병최상견적만성병발증지일,병변가루급중추신경급주위신경,급환자대래불동정도적통고,엄중적심지치잔,사환자상실정상생활능력. 목적 위경호지인식통성당뇨병신경병변(painful diabetic neuropathy,PDN)적위해,병재림상상채취조기예방급유효치료적방법,특작일종술. 내용 종합상관문헌,귀납분석당뇨병인발PDN적발병궤제、림상표현、진단여치료적최신진전. 추향 해병발증득도경엄범관주화심입적인식.
Background Diabetic neuropathy (DN) is one of the most common complications of diabetes mellitus,which could implicate central nervous system and peripheral nervous system,resulting in pain,physical disability and even loss of self-care ability.Objective To provide a clear understanding of this disease and some evidences for prevention and therapy thereof.Content The progress of the mechanisms,clinical manifestations,diagnosis and therapy of the painful diabetic neuropathy(PDN) is summarized in this review.Trend The PDN will draw more attention and deep understanding.