CAJ | 학술논문

目的：为了进一步探讨中老年大面积脑梗死疾病的非手术治疗效果，探讨脑梗死伤残率与脑梗死后抑郁症之间的关系。方法根据我院2007年8月～2013年8月间收治的中老年大面积脑梗死疾病患者的临床资料，选取75例伴脑梗死后抑郁症患者，采用抗脑梗死药物以及抗抑郁药物进行治疗，观察患者治疗情况以及脑梗死与脑梗死后抑郁症的相对关系。结果中年患者35例，死亡率为31.43%，残障率为22.86%，患者远期预后较老年组好；老年患者40例，死亡率为37.5%，残障率为30%，患者早期以及伴合并症者死亡率较高，预后差。脑梗死后抑郁症治疗情况：重度患者疗效差，内源性患者疗效差，中轻度患者疗效较佳。脑梗死与脑梗死后抑郁相互作用。结论中老年大面积脑梗死患者采用保守药物治疗效果较为稳定，但存在一定的局限性，与手术治疗相比治疗过程更安全，对患者机体环境要求较低，可做特殊患者以及不适做手术的脑梗死患者一般治疗方式，控制患者抑郁症情况也可降低死亡以及残障率。
목적：위료진일보탐토중노년대면적뇌경사질병적비수술치료효과，탐토뇌경사상잔솔여뇌경사후억욱증지간적관계。방법근거아원2007년8월～2013년8월간수치적중노년대면적뇌경사질병환자적림상자료，선취75례반뇌경사후억욱증환자，채용항뇌경사약물이급항억욱약물진행치료，관찰환자치료정황이급뇌경사여뇌경사후억욱증적상대관계。결과중년환자35례，사망솔위31.43%，잔장솔위22.86%，환자원기예후교노년조호；노년환자40례，사망솔위37.5%，잔장솔위30%，환자조기이급반합병증자사망솔교고，예후차。뇌경사후억욱증치료정황：중도환자료효차，내원성환자료효차，중경도환자료효교가。뇌경사여뇌경사후억욱상호작용。결론중노년대면적뇌경사환자채용보수약물치료효과교위은정，단존재일정적국한성，여수술치료상비치료과정경안전，대환자궤체배경요구교저，가주특수환자이급불괄주수술적뇌경사환자일반치료방식，공제환자억욱증정황야가강저사망이급잔장솔。
Objective To further explore the non-surgical curative effect of massive cerebral infarction for middle-aged and elderly patients, and to analyze the relations between the disability rate of cerebral infarction and cerebral infarction-induced depression. Methods According to the clinical data obtained from middle-aged and elderly patients with massive cerebral infarction who were admitted to our hospital from August 2007 to August 2013,75 patients with cerebral infarction-induced depression were selected and given anti-cerebral infarction drugs and anti-depression drugs for the treatment.The curative effect and the relations between cerebral infarction and depression were observed. Results There were 35 middle-aged patients.Their mortality rate was 31.43%,disability rate was 22.86% and long-term prognosis was better than that of the elderly patients;there were 40 elderly patients. Their mortality rate was 37.5% and the disability rate was 30%. The mortality rate was higher for early stage and complications,and the prognosis was poor. Conclusion Of treating cerebral infarction-induced depression:the curative effect was poor for severe patients and endogenous patients, and better for mild and moderate patients. The cerebral infarction was interacting with cerebral infarction-induced depression. Conclusion The curative effect of conservative medicine is stable for treating massive cerebral infarction for middle-aged and elderly patients,but has certain limitations.Its treatment process is safer than that of a surgical treatment, and it has a lower requirement for patients'health condition.The method can be used as a general treatment for special patients or patients not suitable for surgery.Controlling patients'depression also helps lower mortality and disability rate.