CAJ | 학술논문

目的：评价弥散性血管内凝血（DIC ）患者体内D-二聚体水平，探讨DIC患者应用D-二聚体检查的临床价值。方法对该院收治的30例DIC患者（DIC组）及30例非DIC患者（对照组）进行D-二聚体检测，比较2组患者D-二聚体水平。同时按照DIC分期将30例DIC患者分为高凝期组、消耗性低凝期组及纤溶亢进期组，比较不同时期患者体内D-二聚体的水平并探讨两者间的相关性。结果 D IC组患者D-二聚体水平明显高于对照组患者，差异有统计学意义（t＝11．229，P＝0．000），而纤溶亢进期患者体内D-二聚体水平最高，其次为消耗性低凝期，高凝期最低，差异有统计学意义（Z＝-4．785，P＝0．000）。同时DIC患者体内D-二聚体水平与DIC分期存在显著的正向直线相关关系（R＝0．982，P＝0．000）。结论 DIC患者体内D-二聚体水平明显高于非DIC患者，且DIC不同时期D-二聚体水平也存在差异，可用于对DIC患者病情的预测。
목적：평개미산성혈관내응혈（DIC ）환자체내D-이취체수평，탐토DIC환자응용D-이취체검사적림상개치。방법대해원수치적30례DIC환자（DIC조）급30례비DIC환자（대조조）진행D-이취체검측，비교2조환자D-이취체수평。동시안조DIC분기장30례DIC환자분위고응기조、소모성저응기조급섬용항진기조，비교불동시기환자체내D-이취체적수평병탐토량자간적상관성。결과 D IC조환자D-이취체수평명현고우대조조환자，차이유통계학의의（t＝11．229，P＝0．000），이섬용항진기환자체내D-이취체수평최고，기차위소모성저응기，고응기최저，차이유통계학의의（Z＝-4．785，P＝0．000）。동시DIC환자체내D-이취체수평여DIC분기존재현저적정향직선상관관계（R＝0．982，P＝0．000）。결론 DIC환자체내D-이취체수평명현고우비DIC환자，차DIC불동시기D-이취체수평야존재차이，가용우대DIC환자병정적예측。
Objective To evaluate the amount of D-2 dimer in patients with disseminated intravascular coagu-lation(DIC) ,and explore the clinical value of D-2 dimer examination in patients with DIC .Methods D-2 dimer exami-nation was taken on 30 cases of DIC patients (DIC group) and 30 cases of non DIC patients (control group) in our hospital ,and DIC levels of the two groups were compared .30 cases of DIC were divided into three groups :high coag-ulation stage group ,consumption of low freezing group and fibrinolytic stage ,according to DIC staging at the same time ,the amount of D-2 dimer in patients with disseminated intravascular coagulation (DIC) in different period was compared and the relationship between them were explored .Results The amount of D-2 dimer in patients with DIC were higher than the control group(t=11 .229 ,P=0 .000) ,which was the highest in fibrinolytic stage patients and the second in low freezing consumption period and the lowest hypercoagulable period (Z= -4 .785 ,P= 0 .000) .At the same time ,DIC dimer levels and DIC stage in patients with D-2 had positive linear correlation (R=0 .982 ,P=0 .000) .Conclusion The amount of D-2 dimer in DIC patients was significantly higher than non DIC patients ,and the amount of D-2 dimer has differences in different DIC stages ,which can be used in the prediction of DIC patients .