CAJ | 학술논문

目的：对高敏C反应蛋白(hs-CRP)、超敏肌钙蛋白T(TnT-hs)在不稳定型心绞痛患者危险分层中的临床效果进行探析,以期为临床实际中应用提供一定的指导。方法试验对象为本院于2011年2月~2012年7月收治的170例不稳定型心绞痛患者。在收治后的1 d内,对患者进行血液hs-CRP、TnT-hs水平的检测。根据TnT-hs浓度水平,将患者分为阴性组(108例)和阳性组(62例)两组,分别对患者行心电图(ECG)检测。规范治疗后,对各患者进行为期1年以上的随访,对患者可能发生的心血管病事件(如恶性心律失常、急性心肌梗死、猝死等)进行统计。结果行ECG后,阴性组中有0例(0)ST段升高,47例(43.5%)ST段下降和(或)T波倒置；阳性组中有3例(4.8%)ST段升高,38例(61.3%) ST段下降和(或)T波倒置。结论利用hs-CRP、TnT-hs水平对不稳定型心绞痛患者进行危险分层,对于不稳定型心绞痛的诊断、治疗以及预后具有重要的作用。
목적：대고민C반응단백(hs-CRP)、초민기개단백T(TnT-hs)재불은정형심교통환자위험분층중적림상효과진행탐석,이기위림상실제중응용제공일정적지도。방법시험대상위본원우2011년2월~2012년7월수치적170례불은정형심교통환자。재수치후적1 d내,대환자진행혈액hs-CRP、TnT-hs수평적검측。근거TnT-hs농도수평,장환자분위음성조(108례)화양성조(62례)량조,분별대환자행심전도(ECG)검측。규범치료후,대각환자진행위기1년이상적수방,대환자가능발생적심혈관병사건(여악성심률실상、급성심기경사、졸사등)진행통계。결과행ECG후,음성조중유0례(0)ST단승고,47례(43.5%)ST단하강화(혹)T파도치；양성조중유3례(4.8%)ST단승고,38례(61.3%) ST단하강화(혹)T파도치。결론이용hs-CRP、TnT-hs수평대불은정형심교통환자진행위험분층,대우불은정형심교통적진단、치료이급예후구유중요적작용。
Objective To explore the application of hs CRP and TnT-hs for risk stratification of patients with unstable angina pectoris, in order to offer some guidance for the clinical practice application. Methods From Feburary 2011 to July 2012, The 170 patients with unstable angina accepted in our hospital. Within 1 day after admission, the hs-CRP of patients in blood and the TnT-hs level was detected. According to TnT-hs concentration level, they could be divided into negative group (108 cases) and the positive group (62 cases);before patients go through the standard therapy. Results The ECG and the negative group (0%), elevated ST segment 0 people, 47 (43.5%), ST segment and/or T wave inversion;positive group of three people (4.8%) in the elevated ST segment, 38 (61.3%), ST segment and/or T wave inversion. Conclusion Using the hs CRP, TnT-hs level for risk stratification in patients with unstable angina pectoris is crucial for unstable angina pectorisdiagnosis, treatment and prognosis of the disease. The application is worthy of clinical application.