CAJ | 학술논문

目的：观察银杏叶片治疗血瘀型正常高值血压的临床疗效。方法选择2011年9月-2013年9月在天津市红桥医院就诊的伴有头晕、头痛症状的正常高值血压（收缩压120~139 mm Hg/舒张压80~89 mm Hg）患者，采用开放型单向质反应序贯试验设计，在改善生活方式的基础上，治疗组和对照组分别给予银杏叶片或银杏叶片模拟剂，连续治疗两周，观察治疗前后血压恢复及中医证候积分改善情况，依据试验结果绘制序贯试验图。结果在血压恢复情况的观察中，治疗组第8例触及上界，对照组第6例触及下界；治疗前两组收缩压和舒张压比较，差异均无统计学意义（P＞0.05）；治疗后两组收缩压和舒张压比较，差异均有统计学意义（P＜0.05）。在中医证候积分改善情况的观察中，治疗组第10例触及上界，对照组第3例触及下界；治疗前两组中医证候积分比较，差异无统计学意义（ P＞0.05）；治疗后两组中医证候积分比较，差异有统计学意义（ P＜0.05）。结论银杏叶片能够降低正常高值血压患者血压，改善中医证候，治疗效果显著，值得临床推广。
목적：관찰은행협편치료혈어형정상고치혈압적림상료효。방법선택2011년9월-2013년9월재천진시홍교의원취진적반유두훈、두통증상적정상고치혈압（수축압120~139 mm Hg/서장압80~89 mm Hg）환자，채용개방형단향질반응서관시험설계，재개선생활방식적기출상，치료조화대조조분별급여은행협편혹은행협편모의제，련속치료량주，관찰치료전후혈압회복급중의증후적분개선정황，의거시험결과회제서관시험도。결과재혈압회복정황적관찰중，치료조제8례촉급상계，대조조제6례촉급하계；치료전량조수축압화서장압비교，차이균무통계학의의（P＞0.05）；치료후량조수축압화서장압비교，차이균유통계학의의（P＜0.05）。재중의증후적분개선정황적관찰중，치료조제10례촉급상계，대조조제3례촉급하계；치료전량조중의증후적분비교，차이무통계학의의（ P＞0.05）；치료후량조중의증후적분비교，차이유통계학의의（ P＜0.05）。결론은행협편능구강저정상고치혈압환자혈압，개선중의증후，치료효과현저，치득림상추엄。
Objective To observe the clinical effect of the ginkgo leaf tablets treatment for high level normal blood pressure of blood stasis type. Methods Patients with high level normal blood pressure visiting Tianjin Red Bridge Hospital from September 2011 to September 2013 with dizziness and headache(120-139 mm Hg SBP / 80-89 mm Hg DBP)were recruited in the study of opened type unidirectional qualitive reaction in sequential trials. On the basis of lifestyle improvement,the treat-ment group and control group were administered respectively ginkgo leaf and ginkgo leaf simulation agent for two weeks. At the same time our researchers observed the blood pressure recovery and TCM symptoms before and after treatment and drew the se-quential trials graph. Results About the blood pressure recovery,the eighth case in treatment group reached the upper bound and the sixth case hit a lower bound. There were no significant differences of SBP and DBP between the treatment group and con-trol group before treatment(P>0. 05),but after treatment they became significant(P<0. 05);In the improvement of TCM symptoms,the tenth case in the treatment group reached the upper bound,the third case hit a lower bound. Before treatment the difference of TCM symptoms between the two groups was not significant( P>0. 05 ) but it became significant after that ( P<0. 05). Conclusion Ginkgo leaf tablets can reduce blood pressure in high level normal patients and improve TCM symp-toms. The treatment effect is significant and is worthy of clinical promotion.