CAJ | 학술논문

黄原胶是一种经发酵生产的微生物胞外杂多糖，前期研究发现其对实验性骨关节炎具有治疗作用。本文通过文献回顾并结合我们的研究，对黄原胶的结构性质、可能代谢途径、及药动学研究方法等进行了简要综述，探讨黄原胶注射液药动学的研究策略。
황원효시일충경발효생산적미생물포외잡다당，전기연구발현기대실험성골관절염구유치료작용。본문통과문헌회고병결합아문적연구，대황원효적결구성질、가능대사도경、급약동학연구방법등진행료간요종술，탐토황원효주사액약동학적연구책략。
Xanthan gum (XG) is a natural microbial extracellular heteropolysaccharide. Our previous study indicated intra-articular injection of XG was probably an effective therapeutic method for osteoarthritis. Through the review of relative literatures and our research findings, the properties and the possible metabolism pathways of XG, and research methods of its pharmacokinetics are introduced in this paper, to probe the research strategies for pharmacokinetics of XG injection.