CAJ | 학술논문

目的：探讨CT导向下经皮肺穿刺射频消融治疗肺部肿瘤的有效性、安全性及并发症。方法对不能手术的74例原发肺癌（其中鳞癌23例，腺癌48例，鳞腺癌2例，大细胞癌1例）和14例转移性肺癌共96个病灶（其中最大直径≤3 cm 31个，3~5 cm 56个，>5 cm 9个），在CT导向下行射频消融治疗，术后6个月随访评价疗效。结果88例患者共行134次射频消融治疗，除1例术中癫痫发作中断手术而行二期射频消融治疗外，其余均顺利完成。术后6个月行CT复查，显示96个病灶体积中88个均进行性缩小，肿瘤内大片不规则低密度区，总有效率为91.7%。1年随访有效率为88.0%，1年无疾病进展生存率为95.5豫。气胸发生率为7.9%。结论 CT导向下经皮肺穿刺射频消融治疗肺部肿瘤安全、有效，并发症较少，对不同肿瘤采取科学的射频消融治疗方案可取得较好的疗效。
목적：탐토CT도향하경피폐천자사빈소융치료폐부종류적유효성、안전성급병발증。방법대불능수술적74례원발폐암（기중린암23례，선암48례，린선암2례，대세포암1례）화14례전이성폐암공96개병조（기중최대직경≤3 cm 31개，3~5 cm 56개，>5 cm 9개），재CT도향하행사빈소융치료，술후6개월수방평개료효。결과88례환자공행134차사빈소융치료，제1례술중전간발작중단수술이행이기사빈소융치료외，기여균순리완성。술후6개월행CT복사，현시96개병조체적중88개균진행성축소，종류내대편불규칙저밀도구，총유효솔위91.7%。1년수방유효솔위88.0%，1년무질병진전생존솔위95.5예。기흉발생솔위7.9%。결론 CT도향하경피폐천자사빈소융치료폐부종류안전、유효，병발증교소，대불동종류채취과학적사빈소융치료방안가취득교호적료효。
Objective To evaluate the safety and therapeutic value of CT-guided radiofrequency ablation(RFA)in the treatment of pulmonary malignancies. Methods A total of 88 patients with lung malignancies,who altogether had 96 lesions,were treated using CT-guided RFA. The cohort included 14 cases of metastatic lung carcinoma and 74 cases of primary non-small cell lung cancer (NSCLC),which comprised various pathological types(23 cases of squamous cell carcinoma,48 adenocarcinoma,2 mixed carcinoma and 1 large cell carcinoma)and tumor sizes (≤3 cm,31 cases;3-5 cm,56 cases;>5 cm,9 cases). Results Lesions in most patients became larger and showed fuzzy edges after RFA;some lesions showed bubble-like changes. Follow-up CT at 6 months showed that all 96 lesions had shrunk,with an overall efficacy of 91.6%. The 1-year local control rate was 88.0%,and the 1-year survival rate was 95.5%. Conclusion CT-guided percutaneous RFA is a safe,effective and minimally invasive therapy for treating pulmonary malignancies.