中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2013年
31期
42-43,44
,共3页
原发性肝癌%肝硬化%乙型肝炎病毒%HBV%DNA
原髮性肝癌%肝硬化%乙型肝炎病毒%HBV%DNA
원발성간암%간경화%을형간염병독%HBV%DNA
Primary hepatocellular carcinoma%Liver cirrosis%Hepatitis B virus%HBV- DNA
目的:探讨太原地区原发性肝癌(PHC)的临床特征及相关病因,提高人们对该病的认识,为有效防控该病提供科学依据。方法回顾分析我院200例PHC患者的完整资料,对其年龄、性别、首发症状、相关病因、乙型肝炎病毒(HBV)标志物等临床资料进行分析。结果①200例患者中,男女比例3.5∶1;年龄分布为24~88(58.10±11.42)岁,高发年龄阶段为50~60岁,发患者数占38%;②首发症状缺乏特异性,主要以腹部不适、憋胀或腹痛为主;③PHC患者中75%有HBV感染史,63%合并肝硬化;④PHC患者中,HBeAg阴性的患者多于HBeAg阳性的患者,并且HBV感染主要以“HBsAg(+)、抗-HBe(+)、抗-HBc(+)”为主,占36.5%(73/200);⑤HBV感染者中HBVDNA阳性率62%(93/150),HBV-DNA载量多在105copies/mL以下。结论HCC患者多为男性,50~60岁为高发年龄段,首发症状缺乏特异性,大多有乙肝后肝硬化病史,感染模式以HBsAg、抗-HBe和抗-HBc三项阳性为主,且HBV-DNA载量多在105copies/mL以下。
目的:探討太原地區原髮性肝癌(PHC)的臨床特徵及相關病因,提高人們對該病的認識,為有效防控該病提供科學依據。方法迴顧分析我院200例PHC患者的完整資料,對其年齡、性彆、首髮癥狀、相關病因、乙型肝炎病毒(HBV)標誌物等臨床資料進行分析。結果①200例患者中,男女比例3.5∶1;年齡分佈為24~88(58.10±11.42)歲,高髮年齡階段為50~60歲,髮患者數佔38%;②首髮癥狀缺乏特異性,主要以腹部不適、憋脹或腹痛為主;③PHC患者中75%有HBV感染史,63%閤併肝硬化;④PHC患者中,HBeAg陰性的患者多于HBeAg暘性的患者,併且HBV感染主要以“HBsAg(+)、抗-HBe(+)、抗-HBc(+)”為主,佔36.5%(73/200);⑤HBV感染者中HBVDNA暘性率62%(93/150),HBV-DNA載量多在105copies/mL以下。結論HCC患者多為男性,50~60歲為高髮年齡段,首髮癥狀缺乏特異性,大多有乙肝後肝硬化病史,感染模式以HBsAg、抗-HBe和抗-HBc三項暘性為主,且HBV-DNA載量多在105copies/mL以下。
목적:탐토태원지구원발성간암(PHC)적림상특정급상관병인,제고인문대해병적인식,위유효방공해병제공과학의거。방법회고분석아원200례PHC환자적완정자료,대기년령、성별、수발증상、상관병인、을형간염병독(HBV)표지물등림상자료진행분석。결과①200례환자중,남녀비례3.5∶1;년령분포위24~88(58.10±11.42)세,고발년령계단위50~60세,발환자수점38%;②수발증상결핍특이성,주요이복부불괄、별창혹복통위주;③PHC환자중75%유HBV감염사,63%합병간경화;④PHC환자중,HBeAg음성적환자다우HBeAg양성적환자,병차HBV감염주요이“HBsAg(+)、항-HBe(+)、항-HBc(+)”위주,점36.5%(73/200);⑤HBV감염자중HBVDNA양성솔62%(93/150),HBV-DNA재량다재105copies/mL이하。결론HCC환자다위남성,50~60세위고발년령단,수발증상결핍특이성,대다유을간후간경화병사,감염모식이HBsAg、항-HBe화항-HBc삼항양성위주,차HBV-DNA재량다재105copies/mL이하。
Objective To Explore the Taiyuan area primary hepatocellular carcinoma (PHC) and related etiology clinical features, improve awareness of the disease, in order to provide the scientiifc basis for effective prevention and control of disease. Methods Retrospective analysis of patients in our hospital 200 cases of PHC complete information on its age, sex, initial symptoms, underlying causes, hepatitis B virus (HBV) markers and other clinical data were analyzed. Results ①two hundreds of patients, the male to female ratio 3.5:1; age distribution of 24~88 (58.10±11.42) years, high ages 50 to 60 years, the incidence accounted for 38%; ② the ifrst symptom of the lack of speciifcity resistance, mainly abdominal discomfort, abdominal pain or swelling choke; ③about 75% of PHC patients have HBV infection, 63% of them have cirrhosis Simultaneously; ④PHC patients, HBeAg-negative patients than in HBeAg-positive patients and HBV infection mainly "HBsAg (+), anti-HBe (+), anti-HBc (+)", accounting for 36.5% (73/200); ⑤HBV infection in HBV DNA positive rate was 62% (93/150), HBV-DNA load more in 105copies/ml less. Conclusion PHC patients are mainly male, 50 to 60 years for the high age, the ifrst symptom of the lack of speciifcity, and most had a history of liver cirrosis, infection mode for HBsAg, anti-HBe and anti-HBc positive based, and HBV-DNA load more in 105 copies/ml less.