CAJ | 학술논문

目的：探讨咳嗽变异性哮喘（CVA）患儿发展为典型哮喘的比例及相关危险因素。方法对2009年10月至2010年10月在郑州市儿童医院就诊的86例CVA患儿进行2年随访，计算其中出现喘息的比例，并对相关因素进行统计分析。结果经过2年随访研究，86例CVA患儿中29例患儿发展为典型哮喘，喘息率为33.7%。29例发展为典型哮喘患儿中有18例患儿对尘螨过敏，57例非哮喘患儿中20例对尘螨过敏，两组比较差异有统计学意义（P=0.023）。结论CVA患儿随访2年有33.7%患儿出现喘息，尘螨过敏可能是CVA发展为典型哮喘的危险因素。
목적：탐토해수변이성효천（CVA）환인발전위전형효천적비례급상관위험인소。방법대2009년10월지2010년10월재정주시인동의원취진적86례CVA환인진행2년수방，계산기중출현천식적비례，병대상관인소진행통계분석。결과경과2년수방연구，86례CVA환인중29례환인발전위전형효천，천식솔위33.7%。29례발전위전형효천환인중유18례환인대진만과민，57례비효천환인중20례대진만과민，량조비교차이유통계학의의（P=0.023）。결론CVA환인수방2년유33.7%환인출현천식，진만과민가능시CVA발전위전형효천적위험인소。
Objective To evaluate the predictors for risk of asthma onset from cough variant asthma (CVA).Methods The follow-up study was conducted in Asthma Center of Zhengzhou Children’s Hospital between October 2009 and October 2010. 86 CVA children were recruited into this study. The children had been studied for two years to ascertain whether asthma developed or not. Results After 2 years of follow up assessment, 29(33.7%)of the 86 children with CVA developedasthma. Results of logistic analysis showed that allergic to dust mites (adjusted OR 2.945, P=0.023) was a risk factor for asthma onset from cough variant asthma. Conclusion Sensitive to dust mites may be a risk factor for the development of asthma in children with CVA.