中国实用护理杂志
中國實用護理雜誌
중국실용호리잡지
CHINESE JOURNAL OF PRACTICAL NURSING
2014年
21期
6-8
,共3页
注射用重组人白介素-11%雾化吸入%放射性咽喉炎
註射用重組人白介素-11%霧化吸入%放射性嚥喉炎
주사용중조인백개소-11%무화흡입%방사성인후염
Recombinant human interleukin-11 for injection%Inhaling therapy%Radioactive pharyngitis
目的 探讨重组人白介素-11雾化吸入对头颈部肿瘤患者放射性咽喉炎的疗效.方法 选取161例初诊头颈部肿瘤患者,在知情同意原则下以区组随机化分组原则分为观察组87例,对照组74例.观察组在照射剂量达20Gy时使用重组人白介素-11雾化吸入至放疗结束,对照组在出现放射性咽喉炎时进行常规治疗.采用RTOG标准分别观察2组患者放射性咽喉炎发生和治疗情况.结果 观察组比对照组放射性咽喉炎出现的平均时间滞后、严重程度降低、治愈时间缩短,差异均有统计学意义.结论 重组人白介素-11雾化吸入可防治放射性咽喉炎,效果优于常规治疗,值得进一步研究并临床推广应用.
目的 探討重組人白介素-11霧化吸入對頭頸部腫瘤患者放射性嚥喉炎的療效.方法 選取161例初診頭頸部腫瘤患者,在知情同意原則下以區組隨機化分組原則分為觀察組87例,對照組74例.觀察組在照射劑量達20Gy時使用重組人白介素-11霧化吸入至放療結束,對照組在齣現放射性嚥喉炎時進行常規治療.採用RTOG標準分彆觀察2組患者放射性嚥喉炎髮生和治療情況.結果 觀察組比對照組放射性嚥喉炎齣現的平均時間滯後、嚴重程度降低、治愈時間縮短,差異均有統計學意義.結論 重組人白介素-11霧化吸入可防治放射性嚥喉炎,效果優于常規治療,值得進一步研究併臨床推廣應用.
목적 탐토중조인백개소-11무화흡입대두경부종류환자방사성인후염적료효.방법 선취161례초진두경부종류환자,재지정동의원칙하이구조수궤화분조원칙분위관찰조87례,대조조74례.관찰조재조사제량체20Gy시사용중조인백개소-11무화흡입지방료결속,대조조재출현방사성인후염시진행상규치료.채용RTOG표준분별관찰2조환자방사성인후염발생화치료정황.결과 관찰조비대조조방사성인후염출현적평균시간체후、엄중정도강저、치유시간축단,차이균유통계학의의.결론 중조인백개소-11무화흡입가방치방사성인후염,효과우우상규치료,치득진일보연구병림상추엄응용.
Objective To conduct prospective randomized controlled clinical observation on patients with nasopharyngeal carcinoma under chemotherapy and radiotherapy using inhaling therapy with recombinant human interleukin 11,and the preventing and curing effect of recombinant human interleukin 11 on radiation-induced pharyngitis is evaluated.Methods 161 cases of newly diagnosed patients with head and neck cancer were selected under the principle of informed consent and these 161 cases were divided into the observation group (87 cases) and the control group (74 cases) based on randomization principle.In the observation group,when the dose reached 20Gy,then recombinant human interleukin-11 inhaling therapy was applied `ll the end of radiotherapy,for the control group,conventional treatment was applied in the event of radioactive throat.RTOG criteria were used during the observation in patients with the occurrence and treatment of radioactive pharyngitis.Results When compared with the control group,the average time for radioactivity to appear was prolonged,the severity decreased and the healing time was shortened in the observation group,those data were statistically significant.Conclusions Recombinant human interleukin-11 inhaling therapy can prevent and cure inhalation of radioactive pharyngitis and this therapy is better than conventional treatment.It's worthy of further study and clinical application.
