CAJ | 학술논문

目的：观察血清降钙素原( PCT)、C反应蛋白( CRP)水平对判断慢性阻塞性肺疾病( COPD)患者合并肺炎及其严重程度的意义。方法：将158例COPD患者根据入院病情分为非感染组77例、普通肺炎组58例、重症肺炎组23例，于入院后24h内进行CRP、PCT检测并进行分析比较。结果：非肺炎组、普通肺炎组及重症肺炎组患者血清PCT、CRP水平差异有显著性(P<0.01)，普通肺炎组及重症肺炎组患者PCT与CRP曲线下面积比较有统计学意义(P<0.05)。结论：PCT、CRP对评判COPD患者是否合并肺炎及肺炎严重程度有临床指导意义，其中PCT的指导意义更大。
목적：관찰혈청강개소원( PCT)、C반응단백( CRP)수평대판단만성조새성폐질병( COPD)환자합병폐염급기엄중정도적의의。방법：장158례COPD환자근거입원병정분위비감염조77례、보통폐염조58례、중증폐염조23례，우입원후24h내진행CRP、PCT검측병진행분석비교。결과：비폐염조、보통폐염조급중증폐염조환자혈청PCT、CRP수평차이유현저성(P<0.01)，보통폐염조급중증폐염조환자PCT여CRP곡선하면적비교유통계학의의(P<0.05)。결론：PCT、CRP대평판COPD환자시부합병폐염급폐염엄중정도유림상지도의의，기중PCT적지도의의경대。
Objective:To evaluate significance of serum procalcitonin ( PCT) and C-reactive protein ( CRP) levels in patients with chronic obstructive pulmonary disease combined with pneumonia. Methods:158 patients with chronic obstructive pulmonary dis-ease were divided into three groups:non-pneumonia group (77 patients), common pneumonia group (58 patients) and severe pneu-monia group (23 patients). The serum CRP and PCT levels were determined in the first 24 hours of admission and compared. Results:The PCT and CRP levels in severe pneumonia group were significantly higher than those of non-pneumonia group and common pneumo-nia group (P<0. 01). The PCT and CRP levels in common pneumonia group were significantly higher than those in non-pneumonia group (P<0. 01). The area under the curve of PCT was larger than that of CRP (P<0. 05). Conclusions: The serum PCT and CRP levels are valuable in the patients with chronic obstructive pulmonary disease combined with pneumonia, and the PCT level is more im-portent than CRP.