CAJ | 학술논문

目的：分析骨髓同步涂片与骨髓活检在多发性骨髓瘤诊断及疗效判断中的价值。方法选取2008年3月至2013年1月在该院进行治疗的多发性骨髓瘤患者92例，均进行骨髓活检与骨髓涂片检查，观察增生程度、诊断敏感性、浆细胞浸润度和浆细胞异常细胞形态检出率。结果骨髓活检检出的骨髓增生程度、诊断敏感性、浆细胞浸润度和浆细胞异常细胞形态检出率均明显高于骨髓涂片检验（P＜0．05）。结论骨髓活检在诊断多发性骨髓瘤方面价值高于骨髓涂片，但可以根据患者的具体情况，采用两者联合以提高诊断准确率。
목적：분석골수동보도편여골수활검재다발성골수류진단급료효판단중적개치。방법선취2008년3월지2013년1월재해원진행치료적다발성골수류환자92례，균진행골수활검여골수도편검사，관찰증생정도、진단민감성、장세포침윤도화장세포이상세포형태검출솔。결과골수활검검출적골수증생정도、진단민감성、장세포침윤도화장세포이상세포형태검출솔균명현고우골수도편검험（P＜0．05）。결론골수활검재진단다발성골수류방면개치고우골수도편，단가이근거환자적구체정황，채용량자연합이제고진단준학솔。
Objective To analysis the clinical value of bone marrow biopsy and bone marrow smears in the di-agnosis of multiple myeloma .Methods 92 multiple myeloma patients were selected for this study .They were all re-ceived bone marrow biopsy and bone marrow smears from March 2008 to January 2013 .The proliferating degree ,the sensitivity of the nodular pattern to diagnosis ,the infiltration degree of plasmocyte and the detection rate of abnormal plasmocyte were observed .Results The proliferating degree ,the sensitivity of the nodular pattern to diagnosis ,the infiltration degree of plasmocyte and the detection rate of abnormal plasmocyte of the bone marrow biopsy were high-er than bone marrow smears(P< 0 .05) .Conclusion The clinical value of bone marrow biopsy in the diagnosis of multiple myeloma is higher than bone marrow smears ,however ,we can use bone marrow biopsy combined with bone marrow smears to improve the accuracy rate of diagnosis of multiple myeloma .