中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2014年
9期
1362-1367
,共6页
李世昊%邓强%荀传辉%盛伟斌
李世昊%鄧彊%荀傳輝%盛偉斌
리세호%산강%순전휘%성위빈
植入物%脊柱植入物%数字化骨科%青少年特发性脊柱侧凸%失平衡%Lenke Ⅱ型%冠状面%危险因素%内固定%并发症%融合
植入物%脊柱植入物%數字化骨科%青少年特髮性脊柱側凸%失平衡%Lenke Ⅱ型%冠狀麵%危險因素%內固定%併髮癥%融閤
식입물%척주식입물%수자화골과%청소년특발성척주측철%실평형%Lenke Ⅱ형%관상면%위험인소%내고정%병발증%융합
internal fixator%scoliosis%regression analysis%linear model
背景：青少年特发性脊柱侧凸是目前临床上影响青少年身体外观的常见病，但通过 Logistic 回归方程来分析固定后冠状面失平衡目前尚缺乏报道。<br> 目的：探讨Lenke Ⅱ型青少年特发性脊柱侧凸患者固定后冠状面失平衡的原因。<br> 方法：对新疆医科大学第一附属医院脊柱外科2001年1月至2012年11月收治的141例Lenke Ⅱ型青少年特发性脊柱侧凸患者进行多个变量的单因素比较和多因素 Logistic 回归分析，筛选导致青少年特发性脊柱侧凸患者固定后发生冠状面失平衡的危险因素，并构建预测模型。<br> 结果与结论：141例患者中有30例出现固定后冠状面失平衡，占全部受试患者的21.28%。对于Lenke Ⅱ型特发性脊柱侧弯畸形患者，固定前顶椎3-4级Nash-More椎体旋转、4-5级Risser征、主弯矫正率/柔韧性>1、下胸弯Cobb角>70°等易引起固定后冠状面失平衡。多因素Logistic回归分析提示椎体旋转、Risser征、主弯矫正率/柔韧性、下胸弯Cobb角等是Lenke Ⅱ型青少年特发性脊柱侧凸患者固定后发生冠状面失平衡的独立危险因素。预测模型为Y=1/[1+exp(-1.182X 1+1.228X 2+1.671X 3-0.71X 4+0.407)]。
揹景：青少年特髮性脊柱側凸是目前臨床上影響青少年身體外觀的常見病，但通過 Logistic 迴歸方程來分析固定後冠狀麵失平衡目前尚缺乏報道。<br> 目的：探討Lenke Ⅱ型青少年特髮性脊柱側凸患者固定後冠狀麵失平衡的原因。<br> 方法：對新疆醫科大學第一附屬醫院脊柱外科2001年1月至2012年11月收治的141例Lenke Ⅱ型青少年特髮性脊柱側凸患者進行多箇變量的單因素比較和多因素 Logistic 迴歸分析，篩選導緻青少年特髮性脊柱側凸患者固定後髮生冠狀麵失平衡的危險因素，併構建預測模型。<br> 結果與結論：141例患者中有30例齣現固定後冠狀麵失平衡，佔全部受試患者的21.28%。對于Lenke Ⅱ型特髮性脊柱側彎畸形患者，固定前頂椎3-4級Nash-More椎體鏇轉、4-5級Risser徵、主彎矯正率/柔韌性>1、下胸彎Cobb角>70°等易引起固定後冠狀麵失平衡。多因素Logistic迴歸分析提示椎體鏇轉、Risser徵、主彎矯正率/柔韌性、下胸彎Cobb角等是Lenke Ⅱ型青少年特髮性脊柱側凸患者固定後髮生冠狀麵失平衡的獨立危險因素。預測模型為Y=1/[1+exp(-1.182X 1+1.228X 2+1.671X 3-0.71X 4+0.407)]。
배경：청소년특발성척주측철시목전림상상영향청소년신체외관적상견병，단통과 Logistic 회귀방정래분석고정후관상면실평형목전상결핍보도。<br> 목적：탐토Lenke Ⅱ형청소년특발성척주측철환자고정후관상면실평형적원인。<br> 방법：대신강의과대학제일부속의원척주외과2001년1월지2012년11월수치적141례Lenke Ⅱ형청소년특발성척주측철환자진행다개변량적단인소비교화다인소 Logistic 회귀분석，사선도치청소년특발성척주측철환자고정후발생관상면실평형적위험인소，병구건예측모형。<br> 결과여결론：141례환자중유30례출현고정후관상면실평형，점전부수시환자적21.28%。대우Lenke Ⅱ형특발성척주측만기형환자，고정전정추3-4급Nash-More추체선전、4-5급Risser정、주만교정솔/유인성>1、하흉만Cobb각>70°등역인기고정후관상면실평형。다인소Logistic회귀분석제시추체선전、Risser정、주만교정솔/유인성、하흉만Cobb각등시Lenke Ⅱ형청소년특발성척주측철환자고정후발생관상면실평형적독립위험인소。예측모형위Y=1/[1+exp(-1.182X 1+1.228X 2+1.671X 3-0.71X 4+0.407)]。
BACKGROUND:Adolescent idiopathic scoliosis is a common disease that can affect physical appearance of adolescents in the clinic at present. However, there are lacks of studies on coronal plane imbalance after fixation using Logistic regression equation at present. <br> OBJECTIVE:To investigate the reasons for coronal plane imbalance after fixation in patients with Lenke type II adolescent idiopathic scoliosis. <br> METHODS:141 cases of Lenke type II adolescent idiopathic scoliosis admitted by Department of Spinal Surgery of the First Affiliated Hospital of Xinjiang Medical University in China from January 2001 to November 2012 were chosen as subjects. Multivariate single factor and multiple-factor Logistic regression were performed. Risk factors for the coronal plane imbalance after fixation in adolescent idiopathic scoliosis patients were screened, and predictive models were established. <br> RESULTS AND CONCLUSION:Coronal plane imbalance occurred in 30 of the 141 patients, accounting for 21.28%. For Lenke type II adolescent idiopathic scoliosis patients, preoperative apical vertebral Nash-More rotation level 3-4, Risser grade 4-5, major curve correction rate/flexibility>1, lower thoracic Cobb angle>70° were vulnerable to postoperative coronal plane imbalance. Multivariate logistic regression showed that vertebral rotation, Risser grade, major curve correction rate/flexibility, lower thoracic Cobb angle were independent risk factors for postoperative coronal plane imbalance in Lenke type II adolescent idiopathic scoliosis patients. The predictive model was Y=1/[1+exp(-1.182X 1+1.228X 2+1.671X 3-0.71X 4+0.407)].
